Results 21 to 30 of about 13,850 (204)

Differential expression and release of activin A and follistatin in chronic rhinosinusitis with and without nasal polyps [PDF]

PLoS ONE, 2015
Background : Chronic rhinosinusitis with (CRSwNP) and without nasal polyps (CRSsNP) should be regarded as distinct clinical entities based on differential inflammatory mediator and remodeling profiles.
Hu, Guohua, Yang, Yucheng, Van Crombruggen, Koen, Claus Bachert, Bachert, Claus, Zhang, Nan, Feng Lan, Koen Van Crombruggen, Lan, Feng, Suling Hong, Hong, Suling, Yucheng Yang, Guohua Hu, Nan Zhang, Hong Suling, Lan, F, Zhang Nan, Van, Crombruggen K, Hong, S, Yang Yucheng, Yang, Y, Hu, G, Crombruggen Koen Van, Bachert Claus, Lan Feng, Bachert, C,, Hu Guohua, Zhang, N   +27 more
core   +2 more sources

Grip strength as a systems biomarker of aging: neuromuscular junction constraints and biomarker decoupling in gene therapy [PDF]

Frontiers in Aging
Grip strength has emerged as one of the most robust predictors of mortality, disability and healthspan across populations. Yet its predictive validity rests on an often-unstated assumption: that grip strength serves as a passive readout of systemic ...
Patrick E. Sewell, Christopher Jensen
doaj   +2 more sources

Inhibition of mesoderm formation by follistatin [PDF]

Development Genes and Evolution, 1998
Mesoderm induction requires interaction between cells of the animal and vegetal hemispheres of the embryo. Several molecules have been proposed as candidates for mesoderm-inducing signals, with activin a particularly strong candidate. However, it has not been possible to inhibit mesoderm formation in vivo by specifically blocking activin action ...
Marchant, Lorena, Linker, Claudia, Mayor, Roberto   +2 more
openaire   +4 more sources

Follistatin-Like Proteins: Structure, Functions and Biomedical Importance

Biomedicines, 2021
Main forms of cellular signal transmission are known to be autocrine and paracrine signaling. Several cells secrete messengers called autocrine or paracrine agents that can bind the corresponding receptors on the surface of the cells themselves or their ...
Vladimir G. Kukes, Dmitry V. Grishin, Olga K. Parfenova   +2 more
core   +2 more sources

Expression patterns of follistatin and two follistatin-related proteins during mouse development [PDF]

The International Journal of Developmental Biology, 2000
We compared the expression patterns of follistatin and two follistatin-related proteins (FRP and m7365) during early mouse development. m7365 is expressed continuously during preimplantation development, in contrast to FRP and follistatin. At early postimplantation stages, follistatin and 7365 are expressed from E6.0, while FRP is detected from E7.5 ...
Groot, E. de, Feijen, A., Eib, D.W., Zwijsen, A., Sugino, H., Martens, G.J.M., Eijnden-van Raaij, A.J.M. van den   +6 more
openaire   +4 more sources

Potential Utility of Urinary Follistatin as a Non-Invasive Indicator of Acute Tubular Damage in Patients with Acute Kidney Injury

Cells
Activin A is known to impede tubular repair following renal ischemia, whereas exogenous follistatin, an activin A antagonist, has been shown to ameliorate kidney damage in rats.
Daisuke Nagata, Akito Maeshima, Izumi Nagayama, Kaori Takayanagi, Hajime Hasegawa   +4 more
core   +2 more sources

Follistatin-related gene expression, but not follistatin expression, is decreased in human endometrial adenocarcinoma [PDF]

European Journal of Endocrinology, 2004
OBJECTIVE: Activin A is a multifunctional growth and cell differentiation factor produced by normal endometrium, and secreted in high amounts by endometrial adenocarcinoma. In the present study we evaluated the expression of two inhibitory activin A ligands, follistatin and follistatin-related gene (FLRG), in endometrial adenocarcinoma and in age ...
Ciarmela, Pasquapina, Florio, Pasquale, SiguroardÃ3ttir, Matthildur, Toti, Paolo, Maguer-Satta, Veronique, Rimokh, Ruth, Altomare, Aldo, Tosi, Piero, Petraglia, Felice   +8 more
openaire   +4 more sources

Denosumab Versus Zoledronic Acid for Muscle Strength and Physical Performance in Postmenopausal Osteoporosis: A 3‐Year Prospective Study [PDF]

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Osteoporosis and sarcopenia frequently coexist in older adults, yet whether denosumab provides muscle‐related benefits beyond bone remains uncertain. We compared denosumab and zoledronic acid across functional, imaging, biologic and study‐defined sarcopenia outcomes based on an Asian Working Group for Sarcopenia (AWGS) 2025‐informed
Xiangwen Li, Zineng Yuan, Nina Ma, Bijuan Huang, Hongyue Tao, Shuang Chen   +5 more
wiley   +2 more sources

The Role of Follistatin Domains in Follistatin Biological Action [PDF]

Molecular Endocrinology, 2004
Follistatin (FS) is an important regulator of pituitary FSH secretion through its potent ability to bind and bioneutralize activin. It also represents a prototype for binding proteins that control bioavailability of other TGFbeta-related growth factors such as the bone morphogenetic proteins.
Henry T, Keutmann, Alan L, Schneyer, Yisrael, Sidis   +2 more
openaire   +2 more sources

Pre- and Peri-/Post-Compaction Follistatin Treatment Increases In Vitro Production of Cattle Embryos. [PDF]

PLoS ONE, 2017
Our previous studies demonstrated that maternal (oocyte derived) follistatin (FST) expression is positively associated with bovine oocyte competence and exogenous follistatin treatment during the pre-compaction period of development (d 1-3 post ...
Guo Zhenhua, Sandeep K Rajput, Joseph K Folger, Liu Di, Jason G Knott, George W Smith   +5 more
doaj   +1 more source