Results 31 to 40 of about 13,850 (204)
Myostatin and follistatin as monitoring and prognostic biomarkers in dysferlinopathy [PDF]
, 2023 Myostatin is a myokine which acts upon skeletal muscle to inhibit growth and regeneration. Myostatin is endogenously antagonised by follistatin. This study assessed serum myostatin and follistatin concentrations as monitoring or prognostic biomarkers in ...
Mori-Yoshimura, Madoka +67 more
core +3 more sources
, 2023 The above image is derived from the original image of western blots in the article ‘Follistatin-like 1 Prevents Renal Ischemia-Reperfusion Injury by Inhibition of Apoptosis via Upregulating AMPK/PPAR-δ Pathway’.
Ken Chen (14586665)
core +1 more source
Elevated circulating follistatin associates with an increased risk of type 2 diabetes
Nature Communications, 2021 Follistatin promotes in type 2 diabetes (T2D) pathogenesis in model animals and is elevated in patients with T2D. Here the authors report that plasma follistatin associates with increased risk of incident T2D in two longitudinal cohorts, and show that ...
Chuanyan Wu +41 more
doaj +1 more source
Frontiers in Endocrinology, 2023 PurposeFollistatin is a glycoprotein that represses members of the transforming growth factor-β superfamily including activin. Higher follistatin levels have been associated with an increased risk for type 2 diabetes and with polycystic ovary syndrome ...
Marta Díaz +4 more
doaj +1 more source
Frontiers in Endocrinology, 2017 Activin is involved in pituitary hormone regulation and its pituitary actions can be nullified by local production of its binding protein follistatin. In our recent study with grass carp, local release of growth hormone (GH) was shown to induce activin ...
Roger S. K. Fung +4 more
doaj +1 more source
Differential Biosynthesis and Intracellular Transport of Follistatin Isoforms and Follistatin-Like-3 [PDF]
Endocrinology, 2005 Follistatin (FST) and FST-like-3 (FSTL3) are structurally related proteins that bind and neutralize activin and closely related members of the TGFβ superfamily. Three FST isoforms (FST288, FST303, and FST315) are produced from the Fst gene that are primarily secreted proteins. FSTL3 is secreted, but is also observed within the nucleus of most cells. We
Seiichiro, Saito +4 more
openaire +2 more sources
The association of the serum levels of myostatin, follistatin, and interleukin-6 with sarcopenia, and their impacts on survival in patients with hepatocellular carcinoma [PDF]
Clinical and Molecular Hepatology, 2020 Background/Aims The role of serum myokine levels in sarcopenia and the outcome of hepatocellular carcinoma (HCC) patients are not clear. This study investigated the serum levels of myostatin, follistatin, and interleukin-6 (IL-6) in HCC patients and ...
Kanghyug Choi +9 more
doaj +1 more source
Human Follistatin-Related Protein: A Structural Homologue of Follistatin with Nuclear Localization [PDF]
Endocrinology, 2001 Follistatin-related protein is a recently discovered glycoprotein that is highly homologous in both primary sequence and exon/intron domain structure to the activin-binding protein, follistatin. We explored their potential for functional redundancy by investigating the relative affinities and kinetics of their interactions with activin, bone ...
D V, Tortoriello +4 more
openaire +2 more sources
Viruses, 2023 The activin–follistatin system regulates several cellular processes, including differentiation and tumorigenesis. We hypothesized that the immunostaining of βA-activin and follistatin varies in neoplastic cervical lesions.
Victor Jesus Huaringa Payano +7 more
doaj +1 more source
Follistatin and Follistatin Like‐3 Differentially Regulate Adiposity and Glucose Homeostasis [PDF]
Obesity, 2011 Transforming growth factor‐β superfamily ligands, including activin and myostatin, modulate body composition, islet function, and glucose homeostasis. Their bioactivity is controlled by the antagonists follistatin (FST) and FST like‐3 (FSTL3). The hypothesis tested was that FST and FSTL3 have distinct roles in regulating body composition, glucose ...
Melissa L, Brown +7 more
openaire +2 more sources