Regulation of reproduction via tight control of gonadotropin hormone levels. [PDF]
Mammalian reproduction is controlled by the hypothalamic-pituitary-gonadal axis. GnRH from the hypothalamus regulates synthesis and secretion of gonadotropins, LH and FSH, which then control steroidogenesis and gametogenesis. In females, serum LH and FSH
Coss, Djurdjica
core +1 more source
Comparison of the effects of two types of resistance training on the serum levels of factors involved in muscular hypertrophy in healthy young men [PDF]
Background and Purpose: Myostatin and follistatin are key proteins in muscle tissue regulation, growth, and hypertrophy. This study aimed to investigate the effects of two types of resistance training on the serum levels of myostatin and follistatin and ...
Sadegh Cheragh-Birjandi +1 more
doaj +1 more source
Follistatin Is a Novel Chemoattractant for Migration and Invasion of Placental Trophoblasts of Mice
Follistatin (FST) as a gonadal protein is central to the establishment and maintenance of pregnancy. Trophoblasts’ migration and invasion into the endometrium are critical events in placental development.
Jing Li +5 more
doaj +1 more source
Comparison of bioactivities, binding properties and intra-follicular levels of bovine follistatins [PDF]
Five isoforms of follistatin (FST) (Mr 31, 33, 35, 37, 41kDa) were purified from bovine follicular fluid (bFF). Comparison of their activin- and heparan sulphate proteoglycan (HSP)-binding properties and bio-potencies in neutralization of activin-A ...
Boland, Maurice P. +4 more
core +1 more source
Activin A is known to impede tubular repair following renal ischemia, whereas exogenous follistatin, an activin A antagonist, has been shown to ameliorate kidney damage in rats.
Izumi Nagayama +4 more
doaj +1 more source
PACAP induces FSHβ gene expression via EPAC. [PDF]
Gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), are heterodimers of a common α subunit and unique β subunits. Regulation of their levels, primarily by GnRH, is critical for reproductive function.
Coss, Djurdjica, Yeh, Debra M
core
Localization of inhibins and activins in normal endocrine cells and endocrine tumors of the gut and pancreas: an immunohistochemical and in situ hybridization study [PDF]
Activins and inhibins, which belong to the TGF beta family, are composed of different combinations of alpha-, betaA-, and betaB-subunits, resulting in inhibin A (alphabetaA), inhibin B (alphabetaB), activin A (betaAbetaA), activin B (betaBbetaB), and ...
Capella, C +4 more
core +1 more source
Unravelling the Genetic Mechanisms of Litter Traits in a Maternal Line of Pigs
ABSTRACT Reproductive traits related to litter size are the main indicators of reproductive efficiency in pig production and are continuously evaluated for the selection of maternal lines. Several environmental and genetic factors are involved with the development of these traits.
Guilherme Oselame +10 more
wiley +1 more source
With rapid economic development, the prevalence of obesity has increased remarkably worldwide. Obesity can induce a variety of metabolic diseases, such as atherosclerosis, diabetes, hypertension and coronary heart disease, which significantly endanger ...
Haoyu Li +7 more
doaj +1 more source
Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome [PDF]
MRF4 (herculin/Myf-6) is one of the four member MyoD family of transcription factors identified by their ability to enforce skeletal muscle differentiation upon a wide variety of nonmuscle cell types.
Miner, Jeffrey H. +5 more
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