Results 21 to 30 of about 4,249 (125)

Non-invasive fibrosis tools lack clinical utility for identifying advanced fibrosis in Fontan-associated liver disease: a retrospective cohort study. [PDF]

BMJ Open Gastroenterol
Objective Fontan-associated liver disease (FALD) results from haemodynamic changes following the Fontan procedure for congenital heart disease and is associated with poorer outcomes.
Armstrong P, Moriarty A, Hughes R, Mehigan N, Savage R, Walsh K, Russell J, Stewart S.   +7 more
europepmc   +2 more sources

Spontaneously ruptured hepatocellular carcinoma in Fontan-associated liver disease: A case report

SAGE Open Medical Case Reports, 2020
The prognosis of congenital heart disease is dramatically improved by cardiac surgery. The Fontan procedure is the definitive palliative operation for patients with single-ventricle physiology.
Takahiro Kubo, Yosuke Aihara, Hideto Kawaratani, Tadashi Namisaki, Ryuichi Noguchi, Akira Mitoro, Hitoshi Yoshiji   +6 more
doaj   +1 more source

Fontan-Associated Liver Disease: A Review

Annals of Hepatology, 2018
Fontan-associated liver disease is a hepatic disorder arising from hemodynamic changes and systemic venous congestion following Fontan surgery. The histological changes produced in the liver are similar but not equivalent to those seen in other forms of ...
Luis Téllez, Enrique Rodríguez-Santiago, Agustín Albillos   +2 more
doaj   +1 more source

Liver transplantation in an adult patient with hepatocellular carcinoma following liver cirrhosis as a complication of the Fontan procedure -A case report- [PDF]

Anesthesia and Pain Medicine, 2020
Background Fontan-associated liver disease (FALD) is a hepatic disorder caused by hemodynamic changes and systemic venous congestion following the Fontan procedure.
Min-kyung Cho, Ji-Hye Kwon, Mi Sook Gwak, Jae-Won Joh, JiYun Hwang, Gaab Soo Kim   +5 more
doaj   +1 more source

Cross-sectional assessment of haemostatic profile and hepatic dysfunction in Fontan patients

Open Heart, 2021
Background Fontan-associated liver disease is accompanied by a hypercoagulable state. While hepatic dysfunction in Fontan patients is common, its relationship with haemostatic changes and clinical outcomes in this patient population remains unclear ...
Paul Monagle, Vera Ignjatovic, David Winlaw, Thomas L Gentles, Karin du Plessis, Yves d'Udekem, Johannes Breur, Joelle Julius Nicolaas Daems, Chantal Attard, Suelyn Van Den Helm, Thomas G Wilson   +10 more
doaj   +1 more source

Comprehensive Multiomic Analysis Reveals Metabolic Reprogramming Underlying Human Fontan-Associated Liver Disease. [PDF]

J Am Heart Assoc
Background The Fontan operation is the current standard of care for single‐ventricle congenital heart disease. Almost all patients with Fontan operation develop liver fibrosis at a young age, known as Fontan‐associated liver disease (FALD).
Sule R, Hu P, Shoffler C, Petucci C, Wilkins BJ, Rychik J, Pei L.   +6 more
europepmc   +2 more sources

Prognostic Value of Liver and Spleen Stiffness in Patients with Fontan Associated Liver Disease (FALD): A Case Series with Histopathologic Comparison

Journal of Cardiovascular Development and Disease, 2021
The Fontan operation is the current surgical procedure to treat single-ventricle congenital heart disease, by splitting the systemic and pulmonary circulations and thus permitting lifespan to adulthood for the majority of newborns. However, emerging data
Massimo A. Padalino, Liliana Chemello, Luisa Cavalletto, Annalisa Angelini, Marny Fedrigo   +4 more
doaj   +1 more source

Abdominal imaging findings in adult patients with Fontan circulation

Insights into Imaging, 2018
The Fontan procedures, designed to treat paediatric patients with functional single ventricles, have markedly improved the patient’s survival into adulthood.
Tae-Hyung Kim, Hyun Kyung Yang, Hyun-Jung Jang, Shi-Joon Yoo, Korosh Khalili, Tae Kyoung Kim   +5 more
doaj   +1 more source

Selective Use of Pulmonary Vasodilators in Patients with Fontan Physiology

Journal of Interventional Cardiology, 2022
Background. Fontan-associated liver disease is a well-known sequela following the Fontan procedure for patients living with single-ventricle heart disease.
Thomas Glenn, Nicole Duster, Jerry Dwek, Jose Silva-Sepulveda, Howaida G. El-Said   +4 more
doaj   +1 more source

Transient liver elastography in the follow-up of Fontan patients: results of a nation wide survey in Germany

Frontiers in Pediatrics, 2023
IntroductionFontan-palliated patients are at risk for the development of Fontan-associated liver disease (FALD). Currently, there is no consensus on how to stage FALD.
Zora Meyer, Nikolaus Haas, Richard Mühlberg, Annabell Braun, Markus Fischer, Guido Mandilaras   +5 more
doaj   +1 more source