Results 31 to 40 of about 4,249 (125)

Non-invasive Investigations for the Diagnosis of Fontan-Associated Liver Disease in Pediatric and Adult Fontan Patients

Frontiers in Cardiovascular Medicine, 2017
Fontan-associated liver disease (FALD) is a serious complication related to the chronically elevated venous pressure and low cardiac output of this abnormal circulation. However, diagnostic markers for this condition are limited.
Amyna Fidai, Frederic Dallaire, Nanette Alvarez, Yvonne Balon, Robin Clegg, Robin Clegg, Michael Connelly, Frank Dicke, Deborah Fruitman, Joyce Harder, Kimberley Myers, David J. Patton, David J. Patton, Tim Prieur, Erika Vorhies, Robert P. Myers, Steven R. Martin, Steven C. Greenway, Steven C. Greenway   +18 more
doaj   +1 more source

Morphologic Alterations Precede Functional Hepatic Impairment as Determined by 13C-Methacetin Liver Function Breath Test in Adult Fontan Patients

Frontiers in Cardiovascular Medicine, 2021
Objectives: Fontan-associated liver disease (FALD) is the most common end-organ dysfunction affecting up to 70–80% of the Fontan population. The clinical significance of FALD is incompletely understood and no unambiguous correlation between hepatic ...
Anastasia Schleiger, Peter Kramer, Hannes Sallmon, Niklas Jentsch, Marta Pileckaite, Friederike Danne, Marie Schafstedde, Marie Schafstedde, Marie Schafstedde, Hans-Peter Müller, Tobias Müller, Frank Tacke, Maximilian Jara, Martin Stockmann, Felix Berger, Felix Berger, Felix Berger, Stanislav Ovroutski   +17 more
doaj   +1 more source

Doppler ultrasound and 2D shear wave ultrasound elastography for liver fibrosis evaluation in Fontan-associated liver disease. [PDF]

BMC Gastroenterol
Background The Fontan operation improves survival in patients with single ventricle physiology but is associated with Fontan-associated liver disease (FALD), characterized by progressive fibrosis due to prolonged elevated central venous pressure.
Inmutto N, Jantarangkoon A, Nimitrungtawee N, Sriwicha N, Kongkarnka S, Sethasathien S, Srisuwan T.   +6 more
europepmc   +2 more sources

Non-invasive biomarkers of Fontan-associated liver disease

JHEP Reports, 2021
Background & Aims: Fontan-associated liver disease (FALD) has emerged as an important morbidity following surgical palliation of single ventricle congenital heart disease. In this study, non-invasive biomarkers that may be associated with severity of
Juliet Emamaullee, Sara Khan, Carly Weaver, Cameron Goldbeck, George Yanni, Rohit Kohli, Yuri Genyk, Shengmei Zhou, Nick Shillingford, Patrick M. Sullivan, Cheryl Takao, Jon Detterich, Paul F. Kantor, John D. Cleveland, Cynthia Herrington, S. Ram Kumar, Vaughn Starnes, Sarah Badran, Neil D. Patel   +18 more
doaj   +1 more source

Efficacy of Magnetic Resonance Elastography in Fontan-Associated Liver Disease. [PDF]

JGH Open
Aims Many patients develop Fontan‐associated liver disease (FALD) after undergoing the Fontan procedure—a surgical treatment for congenital heart disease such as single ventricle—owing to changes in venous pressure and cardiac output. Liver biopsy is the
Iwaki M, Kobayashi T, Wada N, Saiki Y, Nagai K, Nogami A, Kawai S, Koyama S, Utsunomiya D, Nakajima A, Yoneda M.   +10 more
europepmc   +2 more sources

MicroRNA-29b/c-3p Indicate Advanced Liver Fibrosis/Cirrhosis in Univentricular Heart Patients With and Without Fontan Palliation

Frontiers in Cardiovascular Medicine, 2021
Aim: The present study aims to identify those microRNAs (miRNAs) in patients with univentricular heart (UVH) disease with and without Fontan palliation that may be associated with advanced liver fibrosis/cirrhosis.Materials and Methods: SurePrint™ 8 ...
Masood Abu-Halima, Masood Abu-Halima, Eckart Meese, Mohamad Ali Saleh, Andreas Keller, Hashim Abdul-Khaliq, Tanja Raedle-Hurst   +6 more
doaj   +1 more source

Multiple Liver Nodules in Fontan-Associated Liver Disease. [PDF]

GE Port J Gastroenterol, 2023
Mendes RR, Marques L, Figueiredo PC.
europepmc   +2 more sources

Alcohol use is prevalent among adults with the fontan circulation but does not correlate with liver disease

International Journal of Cardiology Congenital Heart Disease, 2022
Background: Alcohol consumption is associated with an increased risk of liver disease. There are limited studies on the epidemiology of alcohol use and its effects on Fontan-associated liver disease (FALD) in adulthood.
Shravani Chintakindi, Bendelyn Asante Boateng, Irine Vodkin, Nicole Herrick, Maria Moceri, Deborah Raleigh, Edward Wang, Howaida El-Said, Ryan Reeves, Jose Silva Sepulveda, Laith Alshawabkeh   +10 more
doaj   +1 more source

Adequacy and Safety of Liver Biopsy Performed During Cardiac Catheterization in Patients With Fontan and Non-fontan Heart Disease

Gastro Hep Advances
Background and Aims: Liver biopsy is the gold standard for diagnosis of hepatic fibrosis. Biopsy performed during cardiac catheterization is a unique approach performed at few centers.
Edward Cytryn, Peizi Li, Maria Isabel Fiel, Barry A. Love, Ali N. Zaidi, Thomas D. Schiano, Lauren T. Grinspan   +6 more
doaj   +1 more source

Diminished liver microperfusion in Fontan patients: A biexponential DWI study. [PDF]

PLoS ONE, 2017
It has been demonstrated that hepatic apparent diffusion coefficients (ADC) are decreasing in patients with a Fontan circulation. It remains however unclear whether this is a true decrease of molecular diffusion, or rather reflects decreased ...
Hildebrand Dijkstra, Djoeke Wolff, Joost P van Melle, Beatrijs Bartelds, Tineke P Willems, Matthijs Oudkerk, Hans Hillege, Aad P van den Berg, Tjark Ebels, Rolf M F Berger, Paul E Sijens   +10 more
doaj   +1 more source