Results 91 to 100 of about 5,009,898 (283)

Agentes bacterianos asociados a brotes de enfermedades transmitidas por alimentos en La Habana, 2006-2010

Revista Cubana de Higiene y Epidemiología
La detección e investigación de los brotes de enfermedades transmitidas por alimentos constituye uno de los principales retos para el Sistema de Salud Pública.
Yamila Puig Peña, Virginia Leyva Castillo, Brady Antonia Robert Maceo, Yoldrey Pérez Muñoz   +3 more
doaj  

Functional Suppression of SCAP Triggers Endoplasmic Reticulum Stress‐Dependent Ferroptosis by Impairing Cholesterol Metabolism in Gastric Cancer

Advanced Science, EarlyView.
This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu, Guangzhao Pan, Lele Zhang, Xiangliu Chen, Kui Zhang, Yang Lu, Zibo Duan, Aiping Chen, Hailong Shen, Yuxi Zhang, Xiaowu Dong, Jinzhou Huang, Xing Huang, Kai Miao, Qian Hua, Fangfang Tao, Weidong Zhang, Jiang‐Jiang Qin   +17 more
wiley   +1 more source

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

Advanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang, Zhehao Lin, Lu Chen, Ying Ni, Jun Zhou, Wenjuan Zhang, Huilin Wang, Peifeng Ying, Xiu Lu, Kai Wang, Qingran Kong, Naxin Xu, Dingsheng Zhao, Jianwei Li, Guohui Zhong, Xingchen Meng, Sarkawt Hamad, Junmeng Zheng, Yuan Fu, Rongjiang Qin, Xuran Chu, Shangxuan Li, Youyou Li, Yili Wu, Yi Wang, Weihong Song, Yingxian Li, Shukuan Ling   +27 more
wiley   +1 more source

An Outbreak of Staphylococcal Food Poisoning Occurs at Low Literacy Girl High School Rajpipala, Narmada District

National Journal of Community Medicine, 2019
Background Food borne diseases including food borne intoxication and infection are term applied a disease caused by agents that enter body through consumption of contaminated food.
Monark Vyas, Chandresh Pandya
doaj  

Single‐Cell Profiling Identifies SLC2A5‐Mediated Fructose Metabolism as a Vulnerability in Primary CNS Lymphoma

Advanced Science, EarlyView.
Glucose deprivation in the primary CNS lymphoma (PCNSL) tumor microenvironment drives SLC2A5 (encoding GLUT5)‐dependent fructose metabolism in tumor cells, while hypoxia induces HIF‐mediated SLC2A5 expression in tumor‐supportive macrophages, revealing SLC2A5‐driven fructose utilization as a shared and targetable metabolic vulnerability across malignant
Qiaoli Wu, Qianru Zhang, Wenqiang Yan, Lu Sun, Yiran Cui, Bolin Liu, Guoqing Han, Feng Zhang, Ke Pu, Mingchao Zhang, Xiaobing Zhang, Qingguo Li, Gang An, Yuxuan Liu   +13 more
wiley   +1 more source

Real‐Time in Vivo Monitoring of Circulating Endometrial Cells: Uncovering Systemic Dissemination and Temporal Fluctuations in Endometriosis

Advanced Science, EarlyView.
A dual‐color pseudo‐menstrual mouse model enables real‐time tracing of circulating endometrial cells (CECs) from uterine and ectopic sources. The study reveals menstrual‐phase‐dependent, burst‐like CEC release, distinct postoperative behaviors of different CEC origins, and a potential association with prolactin fluctuations, providing an in vivo ...
Shang Wang, Chenyu Hou, Buyun Li, Hongyan Cheng, Xue Ye, Honglan Zhu, Yanmin Li, Rui Chen, Sihan Dong, Yi Li, Huiping Liu, Chen Zhang, Rui Zhang, Hongyi Hou, Xunbin Wei, Xiaohong Chang   +15 more
wiley   +1 more source

Knowledge, attitudes, and practices towards poultry handling and Salmonella risk among households in Beirut, Lebanon

Journal of Agriculture and Food Research
Food-Borne Disease (FBD) is defined as an illness resulting from consuming foods contaminated with bacteria, their toxins, viruses, or parasites. Food poisoning due to improper food handling is a major global public health problem.
Dana Ataya, Christelle F. Iskandar, Samer A. Kharroubi, Mohamad T. Farran   +3 more
doaj   +1 more source

Emerging Food-borne Diseases [PDF]

Journal of Tropical Pediatrics, 1997
openaire   +2 more sources

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

Advanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li, Daishi Li, Danyao Chen, Yating Dian, Lei Yao, Hui Su, Ziyu Guo, Deze Zhao, Zihua Wu, Furong Zeng, Chunfang Zhang, Guangtong Deng   +11 more
wiley   +1 more source

Tick-borne diseases in the North Sea region–A comprehensive overview and recommendations for diagnostics and treatment

As part of the NorthTick project, co-funded by the European Union through the European Regional Development Fund and the North Sea Region Programme, specialists in the field of tick-borne diseases from seven North Sea countries co-operated with patient ...
Lindgren, Per-Eric, Y. Kerlefsen, Lebech, Anne Mette, Dobler, Gerhard, Hovius, Joppe W.,, Fingerle, Volker,, Lernout, Tinne, Kerlefsen, Yvonne,, Vrijlandt, Amber, Mavin, Sally,, Henningsson, Anna J.,, L. Chin, Lim, Chin,, Kerlefsen, Yvonne, Lebech, Anne-Mette,, Lernout, Tinne,, A.M. Lebech, G. Dobler, H. Reiso, Henningsson, Anna J., Lindgren, Per Eric, Mavin, Sally, J.W. Hovius, Dobler, Gerhard,, Fingerle, Volker, S. Mavin, T. Lernout, Lim, Chin, Eikeland, Randi, Lindgren, Per-Eric,, Gynthersen, Rosa M.,, A. Vrijlandt, Lebech, Anne-Mette, Reiso, Harald, Eikeland, Randi,, P.E. Lindgren, Vrijlandt, Amber,, Gynthersen, Rosa M., R. Eikeland, Reiso, Harald,, R.M. Gynthersen, A.J. Henningsson, Hovius, Joppe W., F. Volker   +43 more
core   +1 more source