Results 101 to 110 of about 476,073 (321)

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

open access: yesAdvanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu   +9 more
wiley   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

open access: yesAdvanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He   +10 more
wiley   +1 more source

Nguyen Viet Hung on food-borne diseases and public health shocks in East Asia and the Pacific

open access: yes, 2014
Parallel Sessions 9: Improving Resilience to Shocks in Regional Contexts. Nguyen Viet Hung, Scientist, Food Safety and Zoonoses program, International Livestock Research Institute (ILRI) in Vietnam and Center for Public Health and Ecosystem Research ...
Hung Nguyen-Viet
core  

One health approach of campylobacteriosis in Egypt: An emerging zoonotic disease

open access: yesJournal of Infection in Developing Countries, 2019
World Health Organization (WHO) defined zoonotic diseases as diseases transmitted from animals to humans and vice versa with or without vector, where more than 75% of the human’s diseases have been transmitted from animals or their products ...
Wafaa A Abd El-Ghany
doaj   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

open access: yesAdvanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao   +28 more
wiley   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

open access: yesAdvanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu   +14 more
wiley   +1 more source

Agentes bacterianos asociados a brotes de enfermedades transmitidas por alimentos en La Habana, 2006-2010

open access: yesRevista Cubana de Higiene y Epidemiología
La detección e investigación de los brotes de enfermedades transmitidas por alimentos constituye uno de los principales retos para el Sistema de Salud Pública.
Yamila Puig Peña   +3 more
doaj  

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin   +16 more
wiley   +1 more source

An Outbreak of Staphylococcal Food Poisoning Occurs at Low Literacy Girl High School Rajpipala, Narmada District

open access: yesNational Journal of Community Medicine, 2019
Background Food borne diseases including food borne intoxication and infection are term applied a disease caused by agents that enter body through consumption of contaminated food.
Monark Vyas, Chandresh Pandya
doaj  

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

open access: yesAdvanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang   +9 more
wiley   +1 more source

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