Results 81 to 90 of about 476,073 (321)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Antibiotic resistance and burden of food borne diseases in developing countries

, 2016
The emergence and re-emergence of antibiotic-resistant food-borne bacteria in recent times calls for concerted efforts, especially in developing countries. Children and immuno-compromised individuals suffer most from these pathogens.
Olumide Odeyemi (14745841), Sani, NA (15626252)   +1 more
core  

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

Advanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang, Rui Chen, Yu Chen, Haowen Lu, Yuchen Qian, Zhiheng Gao, Zheming Shen, Xiaofei Zheng, Huilin Yang, Jun Zou, Yusen Qiao   +10 more
wiley   +1 more source

Upcycling Compact Discs Into Ultra‐Stable, Flexible, and Stretchable Nanoporous Gold Electrodes for Enhanced Biosensing Performance

Advanced Materials Technologies, EarlyView.
This article highlights the development of robust and high‐performance flexible and stretchable biosensors that maintain long‐term functionality and optimal electrical conductivity under mechanical deformation, utilizing sustainable and cost‐effective manufacturing principles.
Mousa H. Aldosari, Ahyeon Koh
wiley   +1 more source

Transmission and Characterization of Creutzfeldt–Jakob Disease and Chronic Wasting Disease in the North American Deer Mouse

Viruses
Prion transmission into rodents is essential for understanding prion strains. However, it is often limited by a “species barrier” that makes transmission challenging and complicates the study of animal and human prion diseases. Here, we report that North
Jennifer Myskiw, Lise Lamoureux, Kathy Frost, Rebecca Fox, Jessy A. Slota, Gordon Mitchell, Ben A. Bailey-Elkin, Stephanie A. Booth   +7 more
doaj   +1 more source

Food-Borne Diseases and Techniques to Detect Food-Borne Pathogens and Their Limitations

International Journal of Advance Research and Innovation, 2016
Food safety is a global health concern. Food is one of the major sources of microbial pathogens in the developing regions. Food borne diseases or infections have increased over a year and ultimately resulted into severe health problems. Different type of food borne infections is detected by different type of microbes or pathogens contaminating the food
Bhawana Bhatt, Gaurav Nagar, Sonali Nagar, Nisha Tyagi   +3 more
openaire   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Investigations on Environmental Risk Factors Responsible For High Prevalence of Food Borne Diseases : The case of Temeke Municipal,Dar es Salaam.

, 2015
Food borne diseases encompass a wide spectrum of illnesses and are a growing public health problem worldwide. They are the result of ingestion of foodstuffs contaminated with microorganisms or chemicals.
Rugemalila, Gaspal Audax
core   +1 more source

Does Food Safety Practices At Home Influence Food Borne Illnesses? - A Study in Urban Slum Households, Mysuru

National Journal of Community Medicine, 2018
Introduction: Food handlers have been found to play prominent roles in transmission of food-borne diseases at all stages of food production - handling, preparation, storage and serving of food and can pose a significant public health problem.
Meghana Narendran, Praveen Kulkarni, Renuka M, Narayana Murthy MR   +3 more
doaj  

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source