Results 201 to 210 of about 8,739,765 (306)

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

open access: yesAdvanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren   +6 more
wiley   +1 more source

Tailored Cationic Visible‐Light‐Active Interfaces for Sustainable, Biodegradable Nanofibers With Dual‐Mode Antimicrobial Activity and Robust Electrostatic Particle Capture

open access: yesAdvanced Materials, EarlyView.
Surface co‐functionalization of biodegradable nanofibers with sodium copper chlorophyllin and quaternary ammonium compounds achieves synergistic antimicrobial activity through combined photodynamic and contact‐killing mechanisms. The cationic surface provides humidity‐resistant electrostatic particle capture while maintaining rapid enzymatic ...
Dong Uk Lee   +10 more
wiley   +1 more source

Amphiphilic Non‐Isocyanate Polyurethane Coatings With Tunable Antifouling and Fouling‐Release Performance: A Log‐Ratio Assessment Framework

open access: yesAdvanced Materials Interfaces, EarlyView.
Amphiphilic non‐isocyanate polyurethane (NIPU) coatings containing reactive hydrophobic poly(dimethylsiloxane) (PDMS) and hydrophilic methoxy poly(ethylene glycol) (MPEG) prepolymers for marine antifouling (AF) and fouling‐release (FR) applications were investigated. The coatings were evaluated with a set of representative marine foulants.
Nastaran Shahzadeh   +7 more
wiley   +1 more source

Bilayered PEDOT:PSS–Collagen Scaffolds as Functional Architectures for Tissue Engineering

open access: yesAdvanced Materials Interfaces, EarlyView.
A bilayered scaffold integrates collagen and PEDOT:PSS as distinct yet interconnected 3D matrices, preserving their fibrillar and conductive characteristics. Spatial compartmentalization enables independent tailoring of each domain while maintaining mechanical stability and compatibility with electrochemical monitoring, providing a multifunctional ...
Rasha Nasser   +6 more
wiley   +1 more source

Scalable Fabrication of Chemically Stabilized Gelatin Hydrogel Fibers by Thermal Drawing

open access: yesAdvanced Materials Interfaces, EarlyView.
Scalable processing of hydrogel fibers remains a major challenge. By coupling thermal drawing with Maillard chemistry, a transient viscous‐flow window is created that enables continuous fabrication of microstructured gelatin fibers tens of meters long, while continued in situ crosslinking during drawing stabilizes the fibers for physiological ...
Chaoqun Dong   +5 more
wiley   +1 more source

Reduced Graphene Oxide Enhances the Vascular Organization and Contractile Performance of Fibrin‐Gelatin‐Based Engineered Cardiac Tissue

open access: yesAdvanced Materials Interfaces, EarlyView.
Fibrin–gelatin hydrogels functionalized with reduced graphene oxide create a mechanically stable and bioactive 3D environment for engineered cardiac tissue. The composite matrix promotes endothelial lumen formation, enhances sarcomeric protein expression, and increases contractile performance of embedded cardiomyocytes.
Christoph Kuckelkorn   +5 more
wiley   +1 more source

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