Results 61 to 70 of about 1,328 (234)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

What drives food choices? Sociodemographic predictors in a representative Czech population sample

BMC Public Health
Background Dietary behavior represents a major determinant of population health, contributing substantially to obesity, diabetes, cardiovascular disease, and other non-communicable conditions.
Monika Kunzová, Leona Mužíková
doaj   +1 more source

Omnivores, Flexitarians, Vegetarians, and Vegans Attach Different Importance to Eleven Motives for Daily Food Choice Decisions: Findings from 5111 UK Adults

Foods
Many initiatives aimed at improving population-wide health or providing food sources that are sustainable and environmentally friendly are focused on a switch from primarily meat-based diets to diets that are more vegetable-based.
Sara R. Jaeger, Glenn B. H. Andersen, John Prescott   +2 more
doaj   +1 more source

Food choice motives including sustainability during purchasing are associated with a healthy dietary pattern in French adults

Nutrition Journal, 2017
Background Sustainability has become a greater concern among consumers that may influence their dietary intake. Only a few studies investigated the relationship between sustainable food choice motives and diet and they focused on specific food groups ...
B. Allès, S. Péneau, E. Kesse-Guyot, J. Baudry, S. Hercberg, C. Méjean   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Consumers’ Motives for Eating and Choosing Sweet Baked Products: A Cross-Cultural Segmentation Study

Foods, 2020
This study aimed to examine consumers’ motives for eating and choosing sweet baked products (SBPs). A cross-cultural segmentation study on a South African (SA) and Swiss population sample (n = 216), was implemented using the Motivation for Eating Scale ...
Annchen Mielmann, Thomas A. Brunner
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Vegans personality traits and food choice motives.

, 2020
Vegans personality traits and food choice motives Vegans are a fast-growing group of consumers and the analysis of their personality traits and food choices is becoming increasingly relevant to food market producers, marketers and health professionals ...
Polinskytė, Viktorija,
core  

Prevalence of inadequate fruit and vegetable consumption and associated food choice motives among adults in an urban population in Kerala

Journal of Family Medicine and Primary Care
Background: Existing literature does not account for food choice motives associated with the non-communicable disease risk factor of an unhealthy diet, primarily characterised by inadequate fruit and vegetable consumption, among adults residing in Kochi ...
Shilpa Sara Abraham, K Sreelakshmi Mohandas   +1 more
doaj   +1 more source

Association between combinations of nutritional status and quality of life and food purchasing motives among the elderly in South Korea

Health and Quality of Life Outcomes, 2020
Background In the elderly, nutritional status and quality of life (QOL) could potentially affect food purchasing behaviors. We examined the association between combinations of nutritional status and QOL and food purchasing motives among the elderly ...
Doyeon Kim, Hyunjung Lim
doaj   +1 more source