Results 41 to 50 of about 2,966,727 (307)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Flavor and product messaging are the two most important drivers of electronic cigarette selection in a choice-based task

open access: yesScientific Reports, 2021
Electronic cigarette use—vaping—is increasingly popular. Various product factors may influence an individual’s choice of e-cigarette. To provide an evidence base for e-cigarette regulation, a better understanding of the role different product attributes ...
Allison N. Baker   +2 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Food Preferences in Lambs After Exposure to Flavors in Solid Foods

open access: yes, 1992
The aim of this study was to determine whether experience with onion- or garlic-flavored food early in life affected subsequent intake of foods with those flavors.
Nolte, Dale L, Provenza, Frederick D
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Laser-induced florescence and absorption studies on some food colors and flavors by violet diode lasers

open access: yesResults in Optics
Laser-induced fluorescence (LIF) of nine food colors and flavors (Allura red, Sunest Yellow, Brilliant blue, green color (2 types), orange color, coffee, strawberry and pistachio flavor) have been studied using a compact violet laser operating at 405 nm.
Kazi Monowar Abedin   +1 more
doaj   +1 more source

Early influences on the development of children’s eating behavior

open access: yesFrontiers in Integrative Neuroscience, 2014
As mammals, we begin life consuming only milk, but as omnivores, by late infancy, we must begin to consume a variety of foods to support growth and health. Fortunately, infants are biologically prepared for this dietary transition; we are born preferring
Leann Birch
doaj   +1 more source

The influence of flavoring components on the physicochemical properties of spray-dried high oleic (HO) and tofu line (TL) soymilk powder

open access: yesFrontiers in Food Science and Technology, 2023
With the increased interest in plant-based foods, a growing demand for high protein plant-based alternatives has spiked the food industry. Consumer acceptance of a food product is influenced by the natural flavor or through the addition of familiar ...
P. Singh   +2 more
doaj   +1 more source

What to Know about Food Flavor? A Review [PDF]

open access: yes, 2022
The primary function of flavors is to add taste or aroma to foods, as they have no nutritional properties. According to Flavor and Extract Manufacturers Association (FEMA), flavors have a place in the food supply to meet consumer demand for a variety of ...
Al Saqqa, Ghada S. R.   +1 more
core   +1 more source

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