Results 41 to 50 of about 50,788 (307)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Food safety knowledge, attitudes and practices of institutional food-handlers in Ghana

BMC Public Health, 2017
Background In large scale cooking, food is handled by many individuals, thereby increasing the chances of food contamination due to improper handling. Deliberate or accidental contamination of food during large scale production might endanger the health ...
Fortune Akabanda, Eli Hope Hlortsi, James Owusu-Kwarteng   +2 more
doaj   +1 more source

Determinants of safe food handling practice among food handlers in food establishments, Yeka sub city, Addis Ababa, Ethiopia

Heliyon, 2023
Background: Poor food handling practice is a key cause of foodborne diseases notably in developing countries like Ethiopia. This study aimed to assess food safety knowledge, attitude and practice of food handlers, establishments’ status and determinants ...
Fresenbet Fanta, Meseret Azene, Kifle Habte, Hanna Samson, Aweke Kebede   +4 more
doaj   +1 more source

Gambaran Sikap Penjamah Makanan Tentang Keamanan Pangan Di Rumah Makan Taman Sari Colomadu Karanganyar [PDF]

, 2016
Introduction: Food Insecure can cause a disease called foodborne diseases. Lack of concern about food hygiene by food handlers actors will have an impact on the quality of the food was presented.
, Endang Nur W, SST,M.Si.Med, , Luluk Ria Rakhma, S.GZ,M., Karo, Afrianus   +2 more
core  

Food Safety Knowledge and Practice Among Community in Sg. Pelek, Sepang, Selangor Darul Ehsan [PDF]

, 2016
Food safety is a basic requirement of food quality. It is an increasingly important public health issue to prevent and control food borne illnesses. A cross-sectional study was designed to determine level of knowledge and practice on food safety, to ...
Hamid, S. A. (Sabariah), Mahat, N. A. (Nur), Shi, C. K. (Chong)   +2 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Sanitasi Makanan Minuman dan Pemeriksaan Rectal Swab Penjamah Makanan pada Hotel Arya Duta Medan dan Hotel The Palace Inn Tahun 2013 [PDF]

, 2014
According to Minister of RI No.1098/MENKES/VII/2003, about sanitary hygiene requirements of the food and restaurant, food handlers are people who are directly related to food and equipment ranging from preparation, cleaning, processing, transporting to ...
nurmaini, N. (nurmaini), santi, D. N. (devi), saragih, B. G. (barita)   +2 more
core  

Code of practice for food handler activities [PDF]

Occupational Medicine, 2005
The food industry regulates various aspects of food handler activities, according to legislation and customer expectations. The purpose of this paper is to provide a code of practice which delineates a set of working standards for food handler hygiene, handwashing, use of protective equipment, wearing of jewellery and body piercing.The code was ...
T A, Smith, R P, Kanas, I A, McCoubrey, M E, Belton   +3 more
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Hubungan Pengetahuan dan Sikap dengan Praktik Hygiene Sanitasi Penjamah Makanan di Kecamatan Kadugede Kabupaten Kuningan Tahun 2013 [PDF]

, 2015
The efforts hygiene food sanitation is essential to maintaining public health. Know of 57 places the management of food and beverage in the area Kadugede health center distric examined only 40 paces food management (70,17%) were eligible.
Amalia, I. S. (Icca), Muriawati, D. (Deasy), Rohaeni, E. (Eni)   +2 more
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