Results 61 to 70 of about 16,097 (247)

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Enhancing Logistical Performance in a Colombian Citrus Supply Chain Through Joint Decision Making: A Simulation Study

Logistics
Background: Agriculture plays a key role in Colombia’s economy. However, the sector faces persistent logistics, infrastructure, and supply chain integration challenges that hinder its development.
Juan Camilo Vargas-Muñoz, Flor Angela Sanchez-Nitola, Wilson Adarme Jaimes, Richard Rios   +3 more
doaj   +1 more source

Réappropriation des systèmes alimentaires par les citoyens : une logique de Communs urbains

Netcom, 2017
The purpose of this research note is to understand the notion of Commons in terms of the re-appropriation by citizens of the systems of production and distribution of food. In this reflection we will question the role of digital tools, and above all, the
Myriam Bouré
doaj   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Food Hubs as a Means to Promote Food Security in Post-Secondary Institutions: A Scoping Review. [PDF]

Nutrients, 2022
Murphy RA, Guo YJ, Cordeiro HSMP, Stroshein S, Hamilton C, Kozicky S.   +5 more
europepmc   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

Safe and welcoming “warm hubs”: Building social connections and inclusion in Welsh communities

Journal of Community Safety and Well-Being
This article is based on research into the development of “warm hubs” in one Welsh city where community organizations and public buildings offered a warm place to access refreshments, food and local support.
Ella C. Rabaiotti
doaj   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Pemetaan struktur kelembagaan food hub pada rantai pasok hortikultura sebagai pusat pangan daerah yang berkelanjutan

Agrointek
Food supply chain problems remain a critical issue that has the potential to disrupt food security and resilience, especially in the horticulture sub-sector.
Rudi Kresna, Wawan Gunawan, Dini Siti Hanifah, Ajat Sudrajat, Fairuz Labibah, Gabriel Toen Toen Sahat Tua Situngkir   +5 more
doaj   +1 more source