Results 81 to 90 of about 17,331 (269)

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

Fostering innovation in Arctic food industries

open access: yesCanadian Food Studies
This Field Report describes the stages in the development of the Arctic Food Innovation Cluster (AFIC). Motivation for AFIC arose during research supported by the Arctic Council’s Sustainable Development Working Group, which found the development of ...
Lisa F. Clark   +2 more
doaj   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

open access: yesAdvanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu   +9 more
wiley   +1 more source

Climate-smart agriculture: community based technology hub’s role in boosting smallholders farmers yields in Tanzania

open access: yesCogent Food & Agriculture
Global food security is increasingly jeopardized by climate-induced rainfall volatility, which disproportionately affects nations reliant on traditional agriculture.
Yuslida John
doaj   +1 more source

THE ECONOMIC PAMPHLETEER: Competition Versus Cooperation

open access: yesJournal of Agriculture, Food Systems, and Community Development, 2016
First paragraphs: Cooperation has emerged as a new watchword of the sustainability movement. Those who are concerned about sustainability are encouraged to cooperate rather than compete.
John Ikerd
doaj   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

open access: yesAdvanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang   +11 more
wiley   +1 more source

The Urban Food Hubs Solution: Building Capacity in Urban Communities

open access: yes, 2017
Access to affordable fresh food is an ongoing challenge for underserved urban neighborhoods across the United States. Several are designated food deserts with no access to a full-service grocery store within a one-mile radius.
O’Hara, Sabine
core   +2 more sources

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

open access: yesAdvanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel   +15 more
wiley   +1 more source

FOOD DELIVERY SERVICES "HUNGRY HUB"

open access: yes
The emergence of digital platforms has revolutionized the food industry, with food delivery services becoming increasingly prevalent worldwide. This paper examines the dynamics, trends, and impacts of food delivery services on consumers, restaurants, and the broader food ecosystem.
Mashamina Rohan   +3 more
openaire   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

open access: yesAdvanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu   +11 more
wiley   +1 more source

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