Results 71 to 80 of about 16,097 (247)

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

A Primer on Local Food Systems

Journal of Agriculture, Food Systems, and Community Development, 2018
First paragraph: Jennifer Robinson and James Farmer’s Selling Local: Why Local Food Movements Matter consoli­dates decades of research on the local food move­ment, drawing attention to the array of local food developments in the U.S.
Amber A. Heckelman
doaj   +1 more source

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, EarlyView.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

Enhancing resilience and sustainable operational performance in food hubs business model framework for disaster-prone areas

Frontiers in Sustainable Food Systems
Food systems in disaster-prone areas face recurrent systemic disruptions that threaten sustainability in a long-term, especially in disaster-prone areas and agricultural production centres.
Fernianda Rahayu Hermiatin, Tomy Perdana, Bhakti Stephan Onggo, Agriani Hermita Sadeli   +3 more
doaj   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Climate-smart agriculture: community based technology hub’s role in boosting smallholders farmers yields in Tanzania

Cogent Food & Agriculture
Global food security is increasingly jeopardized by climate-induced rainfall volatility, which disproportionately affects nations reliant on traditional agriculture.
Yuslida John
doaj   +1 more source

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

Advanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li, Xin‐Yuan Zhao, Min Zhang, Zhuang‐Feng Weng, Xiao‐Ran Guo, Ying‐Fang Liu, Qiao‐Ping Wang, Huan‐Huan Liang   +7 more
wiley   +1 more source

Fostering innovation in Arctic food industries

Canadian Food Studies
This Field Report describes the stages in the development of the Arctic Food Innovation Cluster (AFIC). Motivation for AFIC arose during research supported by the Arctic Council’s Sustainable Development Working Group, which found the development of ...
Lisa F. Clark, Andrey Mineev, David Natcher   +2 more
doaj   +1 more source

THE ECONOMIC PAMPHLETEER: Competition Versus Cooperation

Journal of Agriculture, Food Systems, and Community Development, 2016
First paragraphs: Cooperation has emerged as a new watchword of the sustainability movement. Those who are concerned about sustainability are encouraged to cooperate rather than compete.
John Ikerd
doaj   +1 more source

FOOD DELIVERY SERVICES "HUNGRY HUB"

The emergence of digital platforms has revolutionized the food industry, with food delivery services becoming increasingly prevalent worldwide. This paper examines the dynamics, trends, and impacts of food delivery services on consumers, restaurants, and the broader food ecosystem.
Mashamina Rohan, Bhokya Anurag, Dr. K. Sreekala, Mrs. N. Musrat Sultana   +3 more
openaire   +1 more source