Results 71 to 80 of about 2,984,281 (225)

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Enhancing resilience and sustainable operational performance in food hubs business model framework for disaster-prone areas

Frontiers in Sustainable Food Systems
Food systems in disaster-prone areas face recurrent systemic disruptions that threaten sustainability in a long-term, especially in disaster-prone areas and agricultural production centres.
Fernianda Rahayu Hermiatin, Tomy Perdana, Bhakti Stephan Onggo, Agriani Hermita Sadeli   +3 more
doaj   +1 more source

A Primer on Local Food Systems

Journal of Agriculture, Food Systems, and Community Development, 2018
First paragraph: Jennifer Robinson and James Farmer’s Selling Local: Why Local Food Movements Matter consoli­dates decades of research on the local food move­ment, drawing attention to the array of local food developments in the U.S.
Amber A. Heckelman
doaj   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

Food Hubs in the UK: Where are we and what next?

, 2019
Food hubs are proliferating. But what exactly are they? What are they for? And why do we need them? This Discussion Paper, based on collaborative work involving local food practitioners and academic researchers, aims to answer some of these questions.
Reynolds, C., Guzman, P.
core   +4 more sources

Climate-smart agriculture: community based technology hub’s role in boosting smallholders farmers yields in Tanzania

Cogent Food & Agriculture
Global food security is increasingly jeopardized by climate-induced rainfall volatility, which disproportionately affects nations reliant on traditional agriculture.
Yuslida John
doaj   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Fostering innovation in Arctic food industries

Canadian Food Studies
This Field Report describes the stages in the development of the Arctic Food Innovation Cluster (AFIC). Motivation for AFIC arose during research supported by the Arctic Council’s Sustainable Development Working Group, which found the development of ...
Lisa F. Clark, Andrey Mineev, David Natcher   +2 more
doaj   +1 more source

Building an Urban Food System Through UDC Food Hubs

, 2018
The Landgrant College of the University of the District of Columbia embodies the university's unique mission as the only exclusively urban land-grant university in the United States.
Dwane Jones, Harris B. Trobman, Sabine O'Hara   +2 more
core   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source