Results 101 to 110 of about 3,075,206 (240)

Multiple child food hypersensitivity impacts positive adjustment in parents

open access: yes, 2017
© 2017, Springer Science+Business Media New York. The physical impacts of food hypersensitivities (e.g. food allergy, food intolerance) encompass wide ranging but individually specific reactions.
Karena J. Burke   +5 more
core   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Food hypersensitivity and feline hyperaesthesia syndrome (FHS): A case report. [PDF]

open access: yesVet Med (Praha), 2021
Ruiz-Suarez N   +4 more
europepmc   +1 more source

Measurements of eosinophil activation before and after food challenges in adults with food hypersensitivity

open access: yes, 2006
Background: Objective assessment of inflammatory reactions in the gastrointestinal tract could be useful in the diagnosis of food hypersensitivity. The aim of the present study was to investigate the involvement of eosinophils and mast cells in the ...
Magnusson, Jenny   +23 more
core   +1 more source

Translational development of crisugabalin for neuropathic pain

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Crisugabalin (HSK16149) is a next‐generation α2δ ligand developed to preserve the mechanistic rationale of gabapentinoids while refining target engagement and exposure‐related tolerability constraints. We performed a translational review of molecular/structural studies, in vivo pharmacology and behavioural safety assessments, phase I clinical ...
Rafael Batista João   +5 more
wiley   +1 more source

Mini-AQLQ- and ACT-scores in relation to perceived food hypersensitivity and IgE sensitization status.

open access: yes, 2015
Mini-AQLQ- and ACT-scores in relation to perceived food hypersensitivity and IgE sensitization status.
Lennart Nordvall (311579)   +6 more
core   +1 more source

Pharmacokinetics and safety of a modified‐release psilocybin formulation: A SAD Phase I trial in normal‐weight and overweight/obese participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the safety, tolerability and pharmacokinetics of a novel oral modified‐release psilocybin formulation (REL‐P11) in normal‐weight and overweight/obese healthy adults and to assess its suitability for controlled, subperceptual exposure, in light of emerging evidence supporting serotonergic modulation in metabolic ...
Anna Signor   +11 more
wiley   +1 more source

A Safe and Effective Method for Wheat Oral Immunotherapy

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2017
At present the only available management for food allergy is avoidance; however, abstaining from allergic foods can affect the quality of life. Oral Immunotherapy (OIT) is an efficient method for increasing tolerance towards food allergens.
Alireza Khayatzadeh   +4 more
doaj  

Unsupervised machine learning for multi‐system adverse event pattern detection in pharmacovigilance: A proof‐of‐concept analysis of fluoroquinolone reports in FAERS

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
. Aims Traditional pharmacovigilance detects single drug–event associations but cannot readily characterize multi‐system adverse‐event patterns such as fluoroquinolone‐associated disability. We evaluated unsupervised machine learning for this purpose, using fluoroquinolones as an exemplar.
Niaz Chalabianloo   +3 more
wiley   +1 more source

The Immunology of Immediate and Delayed Hypersensitivity Reaction to Gluten

open access: yesEuropean Journal of Inflammation, 2008
The immunology of gluten hypersensitivity and celiac disease has been pursued with significant interest in the past 20 years. For the prevention of systemic diseases, most pathogens that gain entry into our bodies must be met with an effective immune ...
A. Vojdani, T. O'Bryan, G.H. Kellermann
doaj   +1 more source

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