Results 91 to 100 of about 3,075,206 (240)

Grouping of asthmatics according to history of perceived food hypersensitivity and IgE sensitization status.

, 2015
Grouping of asthmatics according to history of perceived food hypersensitivity and IgE sensitization status.
Lennart Nordvall (311579), Magnus P. Borres (290059), Christer Janson (83414), Jonas Lidholm (651797), Andrei Malinovschi (168111), Jennifer Johnson (3506621), Kjell Alving (508298)   +6 more
core   +1 more source

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Food hypersensitivity: an examination of factors influencing symptoms and temporal changes in the prevalence of sensitization in an adult sample. [PDF]

Eur J Clin Nutr, 2023
Lam HCY, Neukirch C, Janson C, Garcia-Aymerich J, Clausen M, Idrose NS, Demoly P, Bertelsen RJ, Ruiz LC, Raherison C, Jarvis DL.   +10 more
europepmc   +1 more source

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

The baked side: Cow's milk and egg protein threshold dose distributions in children reacting to baked milk and baked egg

World Allergy Organization Journal
Background: Children allergic to milk and egg, but tolerant to baked products, display higher reactivity thresholds than the general population of children allergic to milk and egg.
Rocco Luigi Valluzzi, MD, Carla Riccardi, MD, Sara Urbani, MD, Davide Ursi, MD, Deborah Zavettieri, MD, Francesco Di Girolamo, PhD, Lamia Dahdah, MD, Veronica Calandrelli, PharmD, Vincenzo Fierro, MD, Alessandro Fiocchi, MD   +9 more
doaj   +1 more source

Early-onset atopic dermatitis and food hypersensitivity increase the risk of atopic march. [PDF]

Clin Exp Allergy, 2022
Pesonen M, Kallio MJT, Ranki A, Siimes MA, Järvinen KM.   +4 more
europepmc   +1 more source

New therapeutic options for metabolic‐associated steatotic liver disease

British Journal of Clinical Pharmacology, EarlyView.
An increasing number of patients are being diagnosed with metabolic dysfunction‐associated steatotic liver disease (MASLD). MASLD results from disturbances in hepatic lipid metabolism and is associated with an increased risk of cirrhosis and hepatocellular carcinoma and significant extrahepatic morbidity, including cardiovascular disease and ...
Tessa Straatmijer, Midas Mulder
wiley   +1 more source

Allergenic protein-induced type I hypersensitivity models: a review

Frontiers in Allergy
ContextType I hypersensitivity affects approximately one-third of the global population. As the pathophysiology underlying the development of type I hypersensitivity (asthma, food allergy, and anaphylactic shock, etc.) is complex and heterogeneous ...
Yanhua Feng, Liangyu Xu, Jinming Zhang, Jinlian Bin, Jinlian Bin, Xialing Pang, Sheng He, Sheng He, Lei Fang, Lei Fang   +9 more
doaj   +1 more source

The forensic implications of food hypersensitivity - a review of cases in United Kingdom courts: January 2014-February 2020. [PDF]

Perspect Public Health, 2022
Gowland MH, Walker MJ.
europepmc   +1 more source