Results 181 to 190 of about 2,663,399 (366)
JPGN Reports, EarlyView.Abstract Ustekinumab (UST) is a monoclonal antibody used in the management of moderate to severe inflammatory bowel disease. While generally well‐tolerated, serious adverse reactions, including hypersensitivity and anaphylaxis, have been documented, specifical following the initial intravenous (IV) dose.
Kennedy Sparling +2 more
wiley +1 more source
JPGN Reports, EarlyView.Abstract Objectives Eosinophilic esophagitis (EoE) is a type 2 cytokine‐mediated chronic inflammatory condition leading to esophageal dysfunction. Dupilumab blocks IL‐4 and IL‐13 signaling, which are key inflammatory mediators in EoE and other allergic disorders.
Sindhura Kasturi +6 more
wiley +1 more source
Food Hypersensitivity and Gut Permeability
, 2015 R. P. K. Ford, J A Walker‐Smith
openalex +1 more source
Frequency and Associated Costs of Anaphylaxis- and Hypersensitivity-Related Adverse Events for Intravenous Iron Products in the USA: An Analysis Using the US Food and Drug Administration Adverse Event Reporting System [PDF]
, 2020 Henry Trumbo +3 more
openalex +1 more source
Overview of Diagnostic Ultrasound Safety
Journal of Ultrasound in Medicine, EarlyView.Ultrasound is widely regarded as a safe imaging modality; however, emerging ultrasound‐based techniques—such as shear wave elastography and contrast‐enhanced ultrasound—operate with varying acoustic output parameters that may approach or exceed traditional diagnostic limits. As these technologies are increasingly integrated into human research studies,
Saubhagya Srivastava +5 more
wiley +1 more source
RTA‐408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Glioblastoma (GBM) is an aggressive brain tumor with poor prognosis owing to its high invasiveness and resistance to therapy. RTA‐408, a synthetic triterpenoid and nuclear factor erythroid 2‐related factor 2 activator, exhibits anti‐inflammatory and anti‐cancer properties; however, its effects on GBM remain unclear. This study investigated the
Hung‐Pei Tsai +6 more
wiley +1 more source
Polyphenolic Activation of Basophils Explains Alcohol Hypersensitivity in AERD
The Laryngoscope, EarlyView.The mechanism behind alcohol sensitivity in AERD has not been previously characterized. This study demonstrates the activation of basophils in patients with CRSwNP and AERD by polyphenolic compounds, but not ethanol. Since these compounds can be found in alcoholic beverages in similar frequencies by which they trigger symptoms, this research provides a
Spencer C. Payne +3 more
wiley +1 more source
Hydrophilic Poly(Iminopyridinium Ylide)s: Defining a New Chemical Space for Poly(ylide)s
Macromolecular Rapid Communications, EarlyView.Poly(iminopyridinium ylide) (PIPY) is reported as an overall charge‐neutral hydrophilic polymer with good water‐solubility, stability across physiologically relevant pH levels, and minimal biomolecular interactions. PIPY shows prevention of insulin fibrillation, which highlights its protein‐stabilizing capacity.
Noël René Schneider +4 more
wiley +1 more source