Results 51 to 60 of about 3,075,206 (240)

HLA-B*5701 screening for hypersensitivity to Abacavir [PDF]

, 2008
Background Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study was designed to establish the effectiveness of prospective HLA-B*5701 screening to prevent the hypersensitivity reaction to ...
Jagel-Guedes, E., Kozyrev, O., Phillips, E., Fitch, N., Thorborn, D., Molina, J-M, Hughes, A., Cid, J.F., Rugina, S., Nolan, D., Carosi, G., Hay, P., Ryan, S., Tomazic, J., Hughes, S., Benbow, A., Mallal, S., Workman, C.   +17 more
core  

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Latin American anaphylaxis registry

World Allergy Organization Journal, 2023
Background: Recent data about clinical features, triggers and management of anaphylaxis in Latin America is lacking. Objective: To provide updated and extended data on anaphylaxis in this region.
Edgardo J. Jares, MD, Victoria Cardona, MD, PHD, R. Maximiliano Gómez, MD, PHD, Jonathan A. Bernstein, M.D, Nelson A. Rosario Filho, MD, Ivan Cherrez-Ojeda, MD, MSC, Luis Felipe Ensina, MD PHD, Alicia De Falco, MD, María C. Díaz, MD, Pierre A. Chávez Vereau, MD, Mara M. Rocha Felix, MD, PHD, Jorge Lavrut, MD, Oscar I. Moreno Laflor, MD, Patricia Latour Staffeld, MD, Pedro Piraino, MD, Perla Alacaraz Duarte, MD, Juan C. Ivancevich, MD, Fabian Dabove, MD, Pedro Giavina-Bianchi, MD, Iván O. Tinoco Moran, MD, Fabiana A. Nunes Oliviera, MD, Silvana Monsell, MD, María V. Souza, MD, Alfonso M. Cepeda, MD, Pablo D. Slullitel, MD, Blanca M. Morfin-Maciel, MD   +25 more
doaj   +1 more source

The Mitogen‐Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis‐Immunity Trade‐Off in Cotton by Regulating Salicylic Acid Biosynthesis

Advanced Science, EarlyView.
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia, Jingshang Wen, Jihang Li, Meina Feng, Yiming He, Ruojun Liu, Qian Liu, Junli Zhang, Kai Cheng, Xiangyu Zhang, Xiao Zhang   +10 more
wiley   +1 more source

The prevalence of parent reported food hypersensitivity at school entry in Malta [PDF]

, 2020
Food hypersensitivity refers to an adverse reaction to food at a dose which is tolerated by the majority of individuals1, which is further classified into allergic and non-allergic food-hypersensitivity.2 Research on food hypersensitivity in young ...
Fallows, Stephen, Porter, Mariella
core   +2 more sources

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

Prevalence (n (%)) of type of food reported as cause of food hypersensitivity (n = 2,307).

, 2014
Prevalence (n (%)) of type of food reported as cause of food hypersensitivity (n = 2,307).
Bertil Forsberg (62630), Thorarinn Gislason (508297), Antonios Patelis (508295), Magnus P. Borres (290059), Christer Janson (83414), Andrei Malinovschi (168111), Peter Burney (59835), Kjell Torén (168121), Kjell Alving (508298), Maria Gunnbjörnsdottir (508296)   +9 more
core   +1 more source

An Investigation Into the Prevalence of Food Hypersensitivity Amongst Children in the Early Years Service in Ireland [PDF]

, 2020
In the early years services in Ireland, the study studied the prevalence of hypersensitivity to food and the associated food among children between the aging of 0 and 12.
Patel, Ruta
core   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

Angewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen, Qiyuan Zhou, Jiaqian Xu, Guangyu Zhu   +3 more
wiley   +2 more sources