Results 51 to 60 of about 60,842 (306)

Features of the cytoprotection of gastric and duodenal mucosa in adolescents with chronic gastroduodenitis on the background of food hypersensitivity

open access: yesZdorovʹe Rebenka, 2018
Background. The cytoprotective properties of the gastrointestinal tract in children with chronic gastroduodenitis on the background of food hypersensitivity remain understudied.
V.S. Berezenko   +4 more
doaj   +1 more source

Anisakis Allergy: Raising Awareness

open access: yesActa Médica Portuguesa, 2022
Introduction: Ingestion of Anisakis is a common cause of allergic reactions to seafood in countries in which undercooked/raw seafood is part of gastronomic traditions.
Tiago Azenha Rama, Diana Silva
doaj   +1 more source

Diminished Signal‐to‐Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1−/y Autism Model

open access: yesAdvanced Science, EarlyView.
This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou   +7 more
wiley   +1 more source

Large-scale survey to estimate the prevalence of disorders for 192 Kennel Club registered breeds [PDF]

open access: yes, 2017
Background Pedigree or purebred dogs are often stated to have high prevalence of disorders which are commonly assumed to be a consequence of inbreeding and selection for exaggerated features.
Evans, K M   +4 more
core   +3 more sources

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

open access: yesAdvanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng   +14 more
wiley   +1 more source

Predisposition of hypersensitivity in patients with exfoliative cheilitis

open access: yesJournal of Dental Sciences, 2022
Background/purpose: Exfoliative cheilitis (EC) is a chronic and reversible inflammatory disease of the lips without definite etiology. Clinically, different types of allergens can be found in exfoliative cheilitis patients, however, few studies have ...
Luyao Cai   +7 more
doaj   +1 more source

Heterogeneous responses of dorsal root ganglion neurons in neuropathies induced by peripheral nerve trauma and the antiretroviral drug stavudine [PDF]

open access: yes, 2014
© 2014 The Authors. European Journal of Pain published by John Wiley & Sons Ltd on behalf of European Pain Federation - EFIC®. Funding sources E.K.B. was funded by a BBSRC PhD studentship. A.N., A.S.C.R. and T.P. were funded by a Wellcome Trust Strategic
Boateng, E K   +4 more
core   +1 more source

Hypersensitivity reactions to food additives [PDF]

open access: yesAllergy, 1987
Only seldom have food additives been shown to cause true allergic (immunological) reactions. Adverse effects due to various pharmacological or other mechanisms are much more common. The individual tolerance may be decreased for one reason or another, and may fluctuate from time to time.
M, Hannuksela, T, Haahtela
openaire   +2 more sources

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

Did food allergy develop in the process of animal evolution?

open access: yesElectronic Physician, 2016
Food allergy is pathophysiologic ally based on stimulation of the immune system at the first exposure, and allergic reactions develop during following exposures. Therefore, memory is the cornerstone of an allergy, as seen in the adaptive immune system.
Seyed Hesamedin Nabavizadeh   +2 more
doaj   +1 more source

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