Results 71 to 80 of about 2,070,415 (312)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The applicability of industrial symbiosis praxis to improving the environmental sustainability of supply chains [PDF]

open access: yes, 2010
The environmental impact of supply chains is a complex problem which involves interconnected and interdependent organisations from different industries, sectors and geographical areas.
Batista, Luciano
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

(R)EXISTÊNCIAS ALIMENTARES: Investigando modos de produção de subjetividade através das práticas alimentares na cidade contemporânea/FOOD RESISTANCE: Investigating modes of production of subjetivity through eating practices in the contemporary city.

open access: yesGeografares, 2018
The article begins with a discussion of the field of studies of Subjectivity (GUATTARI, ROLNIK, 2010), to reflect on subjective modes of production, through eating practices in the context of the contemporary city.
Camila Caires Craveiro
doaj   +1 more source

Best Management Practices to Enhance Water Quality: Who is Adopting Them? [PDF]

open access: yes
This study investigates the determinants affecting producers’ adoption of some Best Management Practices (BMPs). Priors about the signs of certain variables are explicitly accounted for by testing for inequality restrictions through importance sampling ...
Ghazalian, Pascal L.   +2 more
core   +1 more source

Characterisation framework of key policy, regulatory and governance dynamics and impacts upon European food value chains: Fairer trading practices, food integrity, and sustainability collaborations. : VALUMICS project “Understanding Food Value Chains and Network Dynamics” funded by EU Horizon 2020 G.A. No 727243. Deliverable D3.3 [PDF]

open access: yes, 2019
The report provides a framework that categorises the different European Union (EU) policies, laws and governance actions identified as impacting upon food value chains in the defined areas of: fairer trading practices, food integrity (food safety and ...
Barling, David   +3 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Food safety: maximising impact by understanding the food business context [PDF]

open access: yes
In Australia there are 5.4 million cases of food-borne illness annually which costs the community $1.2 billion per annum. As a co-regulator in food safety, local government has a significant interest in ensuring adherence to good food safety practices ...

core  

High Performance HR Practices And Customer Satisfaction: Employee Process Mechanisms [PDF]

open access: yes, 2002
This research examined organizational commitment and customer focus as mediators between HR practices and customer satisfaction of seventy-one work units from twenty-five business units from a single firm in the food service industry.
Gardner, Timothy M.   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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