Increased IgE-Mediated Food Allergy With Food Protein-Induced Allergic Proctocolitis. [PDF]
* Abbreviations: CI — : confidence interval FPIAP — : food protein-induced allergic proctocolitis IgE-FA — : immunoglobulin E–mediated food allergy OR — : odds ratio Immunoglobulin E–mediated food allergy (IgE-FA) can be life-threatening in children, and rates are rising in the United States.1 We now know that
Martin VM +8 more
europepmc +5 more sources
Diagnosis and Management of Food Protein-Induced Allergic Proctocolitis. [PDF]
Food protein-induced allergic proctocolitis (FPIAP) is a frequent cause of rectal bleeding in otherwise healthy infants. Although benign and self-limited, wide variation in diagnostic and management practices often leads to overdiagnosis, unnecessary dietary restriction, and disruption of breastfeeding.
Leney M, Kahale F, Martin VM.
europepmc +3 more sources
Outcomes of Infants With Severe Refractory Food Protein-induced Allergic Proctocolitis Treated With Mesalamine. [PDF]
This retrospective chart review evaluates the outcomes of mesalamine treatment in infants with severe food protein‐induced allergic proctocolitis (FPIAP) and persistent clinical symptoms despite the use of elemental formulas. Patients received mesalamine in a 40–60 mg/kg/d dose for an average of 100 days. This group showed significantly higher rates of
Rojas Gallegos MB, Crissinger KD.
europepmc +4 more sources
In routine pediatric practice, non-IgE-mediated forms of gastrointestinal food allergy are still poorly recognized. This is due to the variety of clinical manifestations, the lack of reliable laboratory diagnostic methods, the unclear association with ...
S. G. Makarova +2 more
doaj +1 more source
Recent topics on gastrointestinal allergic disorders [PDF]
Gastrointestinal (GI) allergies are broadly associated with food allergies and divided into groups based on the degree of allergen-specific immunoglobulin E (IgE) involvement: IgE-mediated, non-IgE-mediated, and mixed.
Yoshiyuki Yamada
doaj +1 more source
Fecal calprotectin and other biomarkers are not prospectively associated with food protein-induced allergic proctocolitis. [PDF]
Abstract Objectives Diagnosis of food protein‐induced allergic proctocolitis (FPIAP) is challenging due to the lack of noninvasive biomarkers. We evaluated fecal calprotectin, eosinophil‐derived neurotoxin (EDN), and zonulin as potential biomarkers for diagnosing FPIAP, while also examining ...
Sun T +9 more
europepmc +3 more sources
Sensitization to common food allergens in infants with food protein-induced allergic proctocolitis: A prospective study. [PDF]
Background: Food protein-induced allergic proctocolitis (FPIAP) is a non-IgE-associated disease, although some evidence exhibits IgE sensitization in a minority of patients. Objectives: This study aimed to determine the prevalence of IgE sensitization to common foods using skin ...
Moghtaderi M +4 more
europepmc +3 more sources
The onset of bloody stools in neonates often results in antibiotic treatment for suspected necrotizing enterocolitis (NEC). Food protein-induced allergic proctocolitis (FPIAP) is an often-neglected differential diagnosis.
Marie Heyne-Pietschmann +6 more
doaj +1 more source
Eosinophil-Derived Neurotoxin, Tumor Necrosis Factor Alpha, and Calprotectin as Non-Invasive Biomarkers of Food Protein-Induced Allergic Proctocolitis in Infants. [PDF]
Diagnosis of non-IgE mediated food allergy presents a special challenge due to lack of a single, non-invasive diagnostic method. We selected three fecal biomarkers of allergic inflammation of gastrointestinal origin in order to improve the diagnostic ...
Rycyk A, Cudowska B, Lebensztejn DM.
europepmc +2 more sources
Hematochezia caused by eosinophilic proctocolitis in a newborn before oral feeding: a case report
Background Hematochezia is a frequent symptom in early infancy. However, it occurs very rarely within the immediate neonatal period, and its occurrence before any oral intake is particularly rare.
Marie-Julie Debuf +3 more
doaj +1 more source

