Results 101 to 110 of about 4,075,567 (351)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Values, attitudes, and goals of future Hungarian food engineers [PDF]

open access: yes
Over the last few decades Hungarian higher education has been radically transformed, and this transformation was implemented to counter the backwardness that previously plagued the education system.
Hajdu, Istvanne, Lakner, Zoltan
core   +1 more source

Effect of traditional and oven roasting on the physicochemical properties of fermented cocoa beans

open access: yesHeliyon, 2018
The objective of this study was to determine the effect of oven and traditional roasting on the polyphenol content, antioxidant activity, lipid quality, proximate composition and mineral content of fermented cocoa beans.
Fabrice Tonfack Djikeng   +10 more
doaj   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

Review of perspectives applied in the assessment of organic food networks [PDF]

open access: yes, 2012
Value is a key concept for understanding how organic food networks function because values are the foundation of the organic production practice, thus value must be given a significant role in assessing and balancing the effects of organic food networks.
Alrøe, Hugo Fjelsted   +2 more
core  

Reproduction and respiration of a climate change indicator species: effect of temperature and variable food in the copepod Centropages chierchiae [PDF]

open access: yes, 2013
The abundance of the calanoid copepod Centropages chierchiae has increased at the northern limits of its distribution in recent decades, mainly due to oceanic climate forcing, suggesting this as a key species in monitoring climate change.
A. Miguel P. Santos   +78 more
core   +1 more source

Fluctuations in phenolic content, ascorbic acid and total carotenoids and antioxidant activity of fruit beverages during storage

open access: yesHeliyon, 2016
Stability of the total phenolic content, ascorbic acid, total carotenoids and antioxidant activity in eight fruit beverages was analyzed. The influence of storage temperature (4, 8 and 11 °C) during the product shelf-life (20 days) was evaluated ...
C. Castro-López   +5 more
doaj   +1 more source

Editorial: Insights into food science and technology in Latin America. [PDF]

open access: yesFront Nutr, 2023
Sánchez-Camargo ADP   +5 more
europepmc   +1 more source

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