Results 91 to 100 of about 265,197 (339)

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

The Marketing of Ultraprocessed Foods in a National Sample of U.S. Supermarket Circulars: A Pilot Study

AJPM Focus, 2022
Introduction: This study aimed to quantify the prevalence of advertisements for ultraprocessed foods and beverages in U.S. supermarket circulars, which are digital and print marketing materials with weekly sales promotions.
Anthony Zhong, BA, Erica L. Kenney, ScD, MPH, Jane Dai, MPH, Mark J. Soto, MA, Sara N. Bleich, PhD   +4 more
doaj  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A mountain food label for Europe?

Revue de Géographie Alpine, 2015
Recent research has demonstrated significant demand for foods from Europe’s mountain areas; the production of these foods delivers significant positive externalities, despite producers facing greater constraints than their lowland equivalents.
Rob McMorran, Fabien Santini, Fatmir Guri, Sergio Gomez-y-Paloma, Martin Price, Olivier Beucherie, Christine Monticelli, Alexia Rouby, Delphine Vitrolles, Guillaume Cloye   +9 more
doaj   +1 more source

Agricultural productivity and food supply to meet increased demands

Future Foods, 2022
Dhu Hemathilake, D. Gunathilake
semanticscholar   +1 more source

Options for reducing food waste by quality-controlled logistics using intelligent packaging along the supply chain

Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment, 2017
Optimising supply chain management can help to reduce food waste. This paper describes how intelligent packaging can be used to reduce food waste when used in supply chain management based on quality-controlled logistics (QCL).
J. Heising, G. Claassen, M. Dekker
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Un label européen pour les produits alimentaires de montagne ?

Revue de Géographie Alpine, 2015
Recent research has demonstrated significant demand for foods from Europe’s mountain areas; the production of these foods delivers significant positive externalities, despite producers facing greater constraints than their lowland equivalents.
Rob McMorran, Fabien Santini, Fatmir Guri, Sergio Gomez-y-Paloma, Martin Price, Olivier Beucherie, Christine Monticelli, Alexia Rouby, Delphine Vitrolles, Guillaume Cloye   +9 more
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Potential of Local Food Use in the Ohio Health Care Industry: An Exploratory Study

Journal of Agriculture, Food Systems, and Community Development, 2016
Institutionalized foodservice in health care is evolving. Some hospitals have introduced local foods as a means of improving health and wellness. Investigation into the hospital foodservice literature, however, leaves unclear what percentage of hospitals
Brian Raison, Scott D. Scheer
doaj   +1 more source