Results 101 to 110 of about 172,792 (314)

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Un label européen pour les produits alimentaires de montagne ?

open access: yesRevue de Géographie Alpine, 2015
Recent research has demonstrated significant demand for foods from Europe’s mountain areas; the production of these foods delivers significant positive externalities, despite producers facing greater constraints than their lowland equivalents.
Rob McMorran   +9 more
doaj   +1 more source

Direct and Intermediated Marketing of Local Foods in the United States [PDF]

open access: yes
This study uses nationally representative data on the marketing of local foods to assess the relative scale of local food marketing channels. This research documents that sales through intermediated marketing channels, such as farmers’ sales to local ...
Vogel, Stephen J., Low, Sarah A.
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

A mountain food label for Europe?

open access: yesRevue de Géographie Alpine, 2015
Recent research has demonstrated significant demand for foods from Europe’s mountain areas; the production of these foods delivers significant positive externalities, despite producers facing greater constraints than their lowland equivalents.
Rob McMorran   +9 more
doaj   +1 more source

Genetically modified foods, trade, and developing countries [PDF]

open access: yes
This paper analyzes price, production and trade consequences of changing consumer preferences regarding the use of genetically modified organisms (GMOs) in food production.
Robinson, Sherman   +2 more
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Potential of Local Food Use in the Ohio Health Care Industry: An Exploratory Study

open access: yesJournal of Agriculture, Food Systems, and Community Development, 2016
Institutionalized foodservice in health care is evolving. Some hospitals have introduced local foods as a means of improving health and wellness. Investigation into the hospital foodservice literature, however, leaves unclear what percentage of hospitals
Brian Raison, Scott D. Scheer
doaj   +1 more source

Perceived Risks of Agro-biotechnology and Organic Food Purchase in the United States [PDF]

open access: yes
This study examined the role of consumers' perceived risks and benefits of agro-biotechnology in shaping the purchase pattern for organic food among US consumers.
Rimal, Arbindra, Moon, Wanki
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy