Results 111 to 120 of about 173,969 (313)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Exploring Alternative Models of Localisation in Food Supply Chains: A Theory of Constraints Approach [PDF]

open access: yes
Local food and the localisation of food are beset by many problems in the UK. We have still yet to agree on a consensus view of the term ‘local food’ despite the call for an enforceable definition. The continued absence of rules around products and their
Heron, Graeme
core  

Supply Chain Control Principles in Local Food Production: A Norwegian Case Study

open access: yesInternational Journal on Food System Dynamics, 2014
Based on an analysis of the supply chain of four producers of local specialty foods, we explore how planning and control principles can be applied to align supply chain capabilities and market requirements.
Heidi C. Dreyer   +4 more
doaj  

Microbial Risks in Food: Evaluation of Implementation of Food Safety Measures

open access: yesHygiene
The process of ensuring the safety of the food supply is dynamic. Both the possibility of contamination and the effectiveness of safety precautions are impacted by changes in the kinds of food consumed, the geographical origins of food products, and the ...
Kashish Rathi   +6 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

A Provisional Framework for Studying Information Connectivity in Food Networks [PDF]

open access: yes
Through a discussion of peculiarities of food supply, involving focus on information connectivity, a preliminary framework is sought that underlines joint responsibility in a complete supply chain of actors working in network context to achieve safe ...
Engelseth, Per, Karlsen, Anniken
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

A STUDY OF FOODS AND FOOD SUPPLY [PDF]

open access: yesFrancis W. Parker School Yearbook, 1915
Jennie Hall   +5 more
openaire   +1 more source

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