Results 121 to 130 of about 499,621 (312)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The Italian food environment may confer protection from hyper-palatable foods: evidence and comparison with the United States

Frontiers in Nutrition
BackgroundMulti-national food corporations may saturate country-level food systems with hyper-palatable foods. However, the degree to which global food corporations have been integrated into country-level food systems may vary. Italy has largely retained
Tera L. Fazzino, Tera L. Fazzino, Carmine Summo, Antonella Pasqualone   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Temporal change in nutritional supply and role of home-based food production: the case of smallholder farmers in Madagascar during the COVID-19 period

Agriculture & Food Security
Background Nutrition is a fundamental aspect of human well-being, yet persistent deficiencies remain prevalent among vulnerable populations. In Madagascar, smallholder farmers experience chronic nutritional insecurity driven by limited dietary diversity ...
Sakiko Shiratori, Risa Nomura, M. G. Dilini Abeysekara, Jules Rafalimanantsoa, Zoniaina Ramahaimandimby, Takeshi Sakurai   +5 more
doaj   +1 more source

Smoking out carcinogens [PDF]

, 2016
Smoked foods are becoming increasingly popular and are being produced by large and small food operations, artisan producers, chefs and consumers themselves.
Baines, David, Griffiths, Huw, Parker, Jane   +2 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Toward a science-based classification of processed foods to support meaningful research and effective health policies

Frontiers in Nutrition
Processed foods have been part of the American diet for decades, with key roles in providing a safe, available, affordable, and nutritious food supply.
Paula R. Trumbo, Paula R. Trumbo, Rachel Bleiweiss-Sande, Jessica K. Campbell, Eric Decker, Adam Drewnowski, John W. Erdman, Mario G. Ferruzzi, Ciaran G. Forde, Michael J. Gibney, Julie M. Hess, David M. Klurfeld, Marie E. Latulippe, Lauren E. O’Connor, Kristin J. Reimers, Barbara J. Rolls, Jackie Schulz, Connie Weaver, Lynn Yu   +18 more
doaj   +1 more source

Case study reducing mycotoxins in Brazilian crops [PDF]

"Mycotoxins are toxic chemical compounds produced by molds, which can have important consequences in human and animal health... The economic consequences of the presence of mycotoxins in food, feed, and agricultural crops can be severe.
Salay, Elisabete
core  

Promoting sustainable consumption and healthy eating: A comparative study among public schools in Denmark, Germany, Finland & Italy [PDF]

, 2010
Since the Ottawa charter on the importance of health promotion in settings the school has been named as one of the most important arenas for interventions to promote physical activity and healthy eating.
He, Chen, Mikkelsen, Bent Egberg
core  

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source