Diagnostic exosomal microRNAs and pathogenic regulatory networks in hepatocellular carcinoma revealed by exosomal RNA sequencing: A case–control study [PDF]
Objective Hepatocellular carcinoma is a leading cause of cancer mortality, and early detection remains limited by the low sensitivity of alpha-fetoprotein.
Xiao Jingwen +6 more
doaj +2 more sources
Regulation of skeletal muscle development and metabolism in broiler chickens by Urolithin A through threonine kinase 1 pathway activation [PDF]
Broiler skeletal muscle dysplasia is characterized by impaired muscle fiber hypertrophy and satellite cell dysfunction, leading to reduced meat yield and increased feed conversion rates, resulting in significant economic losses. With the impending global
Liuting Wu, Leilei Peng, Xiaoling Zhao
doaj +2 more sources
Forkhead box O (FoxO) transcription factors and E3 ubiquitin ligases such as Muscle RING finger 1 (MuRF1) are believed to participate in the regulation of skeletal muscle mass. The function of FoxO transcription factors is regulated by post-translational modifications such as phosphorylation and acetylation.
Ann-Kristin Fjällström +3 more
openalex +5 more sources
The Roles and Regulatory Mechanisms of Tight Junction Protein Cingulin and Transcription Factor Forkhead Box Protein O1 in Human Lung Adenocarcinoma A549 Cells and Normal Lung Epithelial Cells. [PDF]
Ishii D +8 more
europepmc +5 more sources
[Research progress on forkhead box protein O1 and bone metabolism]. [PDF]
Linjing S, Yingying W, Zhen T, Ping G.
europepmc +3 more sources
Fat mass and obesity-associated protein downregulation trigger the activation of the sirtuin 1/forkhead box O1 signaling pathway, drive glycolysis, and promote the progression of renal cell carcinoma. [PDF]
Zhang Z, Zhang J, Zhang R.
europepmc +2 more sources
Agouti related protein (AGRP); forkhead box O1 (FOXO1); G protein–coupled receptor 17 (GPR17) [PDF]
openalex +3 more sources
Systems-wide Experimental and Modeling Analysis of Insulin Signaling through Forkhead Box Protein O1 (FOXO1) in Human Adipocytes, Normally and in Type 2 Diabetes. [PDF]
Rajan MR +4 more
europepmc +3 more sources
Constitutively active FOXO1 diminishes activin induction of Fshb transcription in immortalized gonadotropes. [PDF]
In the present study, we investigate whether the FOXO1 transcription factor modulates activin signaling in pituitary gonadotropes. Our studies show that overexpression of constitutively active FOXO1 decreases activin induction of murine Fshb gene ...
Arriola, David J +4 more
core +11 more sources

