Results 181 to 190 of about 56,919 (302)

Osteochondrosis in horses: An overview of genetic and other factors

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez   +2 more
wiley   +1 more source

Phosphatidic acid induces cytoskeletal rearrangements through the Src‐FAK‐RhoA/ROCK signaling pathway during decidualization

open access: yesThe FEBS Journal, EarlyView.
Decidualization is the process by which human endometrial stromal cells undergo morphological and functional changes to prepare the uterus for embryo implantation and support pregnancy. Our study identifies the phosphatidic acid‐Src‐FAK‐RhoA/ROCK signaling pathway as a critical regulator of the cytoskeletal alterations required for this transformation.
Hyeon‐Jeong Jun   +5 more
wiley   +1 more source

Inhibition of Phosphorylation of a Forkhead Transcription Factor Sensitizes Human Ovarian Cancer Cells to Cisplatin [PDF]

open access: bronze, 2004
Emi Arimoto‐Ishida   +12 more
openalex   +1 more source

Epigenetic control of cell identities from epiblast to gastrulation

open access: yesThe FEBS Journal, EarlyView.
In this review, we present and contextualize current knowledge about the roles of epigenetic modifiers during the development of mouse epiblast to gastrulation stage. The epigenetic regulation of enhancer and promoter elements by DNA methylation, histone modifications, and chromatin accessibility in concert with lineage‐specific transcription factors ...
Katrin M. Schüle, Simone Probst
wiley   +1 more source

CTLA-4–Ig Activates Forkhead Transcription Factors and Protects Dendritic Cells from Oxidative Stress in Nonobese Diabetic Mice [PDF]

open access: bronze, 2004
Francesca Fallarino   +8 more
openalex   +1 more source

Unraveling the functional dynamics of Caenorhabditis elegans stress‐responsive omega class GST‐44

open access: yesThe FEBS Journal, EarlyView.
Omega‐class glutathione S‐transferases (GSTs) are integral to redox regulation and cellular stress responses. This study characterized GST‐44 in Caenorhabditis elegans, revealing its predominant expression in the intestine and excretory H‐cell, with significant upregulation under various stress conditions.
Charlotte Sophia Kaiser   +9 more
wiley   +1 more source

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