Low‐protein diet for chronic kidney disease: Evidence, controversies, and practical guidelines
Abstract The benefits of a low‐protein diet (LPD) in patients with altered kidney function remain controversial. Dietary intake studies are inherently complex and may present numerous biases that must be understood and controlled. Due to these challenges, the scientific evidence in this area remains limited and is subject to dispute.
Denise Mafra+4 more
wiley +1 more source
Gata4expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element [PDF]
Anabel Rojas+5 more
openalex +1 more source
Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye+5 more
wiley +1 more source
Coordination of NF-κB and NFAT Antagonism by the Forkhead Transcription Factor Foxd1 [PDF]
Ling Lin, Stanford L. Peng
openalex +1 more source
Inflammation and mechanical force‐induced bone remodeling
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon+6 more
wiley +1 more source
Expression of the forkhead transcription factor FoxN4 in progenitor cells in the developing Xenopus laevis retina and brain [PDF]
Lisa E. Kelly+2 more
openalex +1 more source
Germ cell and other tumors in individuals with differences in sex development
Abstract Approximately one in 3500 to one in 5100 live‐born infants have atypical external genital development, known as differences in sex development (DSD). In 2005, an expert consensus conference thoroughly reviewed aspects of health care for individuals with DSD.
Selma Feldman Witchel+1 more
wiley +1 more source
Mitochondrial Dysfunction in Aging: Future Therapies and Precision Medicine Approaches
Mitochondria play a critical role in aging and aging‐related diseases. This review systematically explores the mechanisms underlying mitochondrial deterioration during aging and highlights innovative therapeutic strategies for these mitochondrial problems.
Lanlan Jia+4 more
wiley +1 more source
Transcriptional Cross Talk between the Forkhead Transcription Factor Forkhead Box O1A and the Progesterone Receptor Coordinates Cell Cycle Regulation and Differentiation in Human Endometrial Stromal Cells [PDF]
Masashi Takano+14 more
openalex +1 more source