Results 211 to 220 of about 626,933 (316)

Transcription Factor Forkhead Regulates Expression of Antimicrobial Peptides in the Tobacco Hornworm, Manduca sexta [PDF]

, 2017
Xue Zhong, Munmun Chowdhury, Chunfeng Li, Xiao‐Qiang Yu   +3 more
openalex   +1 more source

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

International Journal of Cancer, Volume 158, Issue 6, Page 1464-1480, 15 March 2026.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

Forkhead Box M1 (FoxM1) Gene Is a New STAT3 Transcriptional Factor Target and Is Essential for Proliferation, Survival and DNA Repair of K562 Cell Line

, 2012
André Luiz Mencalha, Renata Binato, Gerson Moura Ferreira, Bárbara Du Rocher, Eliana Abdelhay   +4 more
openalex   +2 more sources

The zebrafish forkhead transcription factor FoxH1/Fast1 is a modulator of Nodal signaling required for organizer formation [PDF]

, 2000
Hans‐Martin Pogoda, Lilianna Solnica‐Krezel, Wolfgang Driever, Dirk Meyer   +3 more
openalex   +1 more source

MicroRNA miR-106a-5p targets forkhead box transcription factor FOXC1 to suppress the cell proliferation, migration, and invasion of ectopic endometrial stromal cells via the PI3K/Akt/mTOR signaling pathway [PDF]

, 2021
Xinyue Zhou, Zhen‐Yu Chen, Lipeng Pei, Jingli Sun   +3 more
openalex   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Identification of BCL2L11 as a Candidate Gene for Hereditary Predisposition to Non‐Medullary Thyroid Cancer Using Familial Whole‐Exome‐Sequencing

Clinical Genetics, Volume 109, Issue 3, Page 458-469, March 2026.
Whole‐exome sequencing of five families with non‐medullary thyroid cancer revealed three candidate genes. Functional analyses confirmed BCL2L11 as a strong candidate gene for hereditary predisposition to non‐medullary thyroid cancer. ABSTRACT Familial non‐medullary thyroid cancer, defined as two or more affected first‐degree relatives, accounts for 3 ...
Duygu Abbasoglu, Mathis Lepage, Nicolas Sonnier, Sandrine Viala, Nancy Uhrhammer, Flora Ponelle‐Chachuat, Anne Cayre, Maud Privat, Mathias Cavaillé, Yannick Bidet   +9 more
wiley   +1 more source

Reversal of Pathological Features of Graves' Orbitopathy by Activation of Forkhead Transcription Factors, FOXOs.

Journal of Clinical Endocrinology and Metabolism, 2016
Lei Zhang, Q. Ji, Fiona Ruge, Carol M. Lane, Daniel S Morris, Andrew R. Tee, Colin M. Dayan, M. Ludgate   +7 more
semanticscholar   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, Volume 16, Issue 2, Page 252-267, February 2026.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

A Human Neural Tube Model Using 4D Self‐Folding Smart Scaffolds

Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
Induced pluripotent stem cells (iPSCs) exhibit features comparable to the inner cell mass of the human embryo. iPSCs are applied to a novel self‐folding 4D‐Neural Tube (4D‐NT) structure that mimics the neurulation process. This 4D‐NT model recapitulates early events of human neural development and represents a platform to explore neurodevelopmental ...
Claudia Dell'Amico, Irene Chiesa, Angela Toffano, Alessio Esposito, Piera Mancini, Chiara Magliaro, Angeliki Louvi, Carmelo De Maria, Marco Onorati   +8 more
wiley   +1 more source