Results 211 to 220 of about 56,919 (302)

FOXP4 Variants Are Associated With Plateau Iris and Angle Closure Glaucoma. [PDF]

Invest Ophthalmol Vis Sci
Presley W, Wang SQ, Guan B, Jeong SH, Bender C, Ward E, Johnson K, Blevins B, Michaels N, Shah M, Moroi SE, Hufnagel RB, Richards JE, Prasov L.   +13 more
europepmc   +1 more source

Transforming Growth Factor‐Beta Signaling in Cancer: Therapeutic Implications, Challenges, and Pathways to Progress

MedComm – Oncology, Volume 4, Issue 3, September 2025.
TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi, Izuchukwu F. Okpalanwaka, Adenike Oyegbesan, Ebenezar Okoyeocha, Mariam Oladejo, Sikiru O. Imodoye   +5 more
wiley   +1 more source

The Human Mucin MUC4 Is Transcriptionally Regulated by Caudal-related Homeobox, Hepatocyte Nuclear Factors, Forkhead Box A, and GATA Endodermal Transcription Factors in Epithelial Cancer Cells [PDF]

, 2007
Nicolas Jonckheere, Audrey Vincent, Michaeöl Perrais, Marie-Paule Ducourouble, Anita Korteland-van Male, Jean-Pierre Aubert, Pascal Pigny, Kermit L. Carraway, Jean‐Noël Freund, Ingrid B. Renes, Isabelle Van Seuningen   +10 more
openalex   +1 more source

Targeting Immune Checkpoints: Basic Signaling Pathways and Clinical Translation in Cancer Therapeutics

MedComm – Oncology, Volume 4, Issue 3, September 2025.
Immune checkpoints in tumor immunotherapy. Ligand binding to the receptor inhibits immune cell function, promotes tumor cell immune escape, and suppresses the immune response. The pathways of action are VISTA‐IGSF11, TIM‐3‐Ceacam1, CD47‐SIRPα, CTLA‐4‐CD80/CD86, PD‐L1‐PD‐1, MHC‐1‐LILRB, and CD24 ‐ Siglec ‐10. There are also other immune checkpoints such
Han Sun, Dan Huang, Huiling Zhang, Mingyuan Dong, Simiao Wang, Man Sun, Jiayi Liu, Yiqi Wang, Xiaojie Qu, Xuefeng Li, Zhaogang Yang   +10 more
wiley   +1 more source

Conversion of a Replication Origin to a Silencer through a Pathway Shared by a Forkhead Transcription Factor and an S Phase Cyclin [PDF]

, 2007
Laurieann Casey, Erin E. Patterson, Ulrika Müller, Catherine A. Fox   +3 more
openalex   +1 more source

Reduced Esterification Rather Than Increased Hydrolysis Is Causative for Loss of Hepatic Retinoids Upon CCl4‐Induced Liver Injury

Liver International, Volume 45, Issue 9, September 2025.
ABSTRACT Background and Aims Advanced liver disease leads to liver fibrosis that is characterised by the activation of non‐parenchymal stellate cells, accumulation of extracellular matrix proteins, and the loss of hepatic vitamin A stores. To date, the molecular mechanisms and enzymes mediating the loss of hepatic vitamin A stores are incompletely ...
Carina Wagner, Kristina Košić, Dominik Bulfon, Johannes Breithofer, Alina Jamnik, Clara Zitta, Paula Horvat, Kim Bilweis, Michael Schupp, Robert Zimmermann, Ulrike Taschler, Achim Lass   +11 more
wiley   +1 more source

DNA probe pulldown screening uncovers O-GlcNAcylation modulation of transcription factor DNA interactions. [PDF]

Sci Rep
Li G, Meng F, Zhong X, Yu K, Zhang N, Zhang K, Huang H, Li W, Zhang J, Wang W, Ren Y, Liu Y.   +11 more
europepmc   +1 more source

Two forkhead transcription factors regulate the division of cardiac progenitor cells by a Polo-dependent pathway. [PDF]

Dev Cell, 2012
Ahmad SM, Tansey TR, Busser BW, Nolte MT, Jeffries N, Gisselbrecht SS, Rusan NM, Michelson AM.   +7 more
europepmc   +1 more source

Beyond the Binary: Controlling Natural Sex‐Change in Hermaphroditic Fishes

Reviews in Aquaculture, Volume 17, Issue 4, September 2025.
ABSTRACT Sex‐change in hermaphroditic fishes is a complex but natural biological phenomenon that has significant implications for aquaculture fingerling production, selective breeding, and grow‐out. Understanding the physiological, endocrinological, and molecular pathways underlying hermaphroditism in fishes offers unique opportunities to manipulate ...
Roni Chandra Mondal, Jarrod L. Guppy, Maria A. Villacis‐Escobar, Dean R. Jerry   +3 more
wiley   +1 more source

A high-content screen identifies inhibitors of nuclear export of forkhead transcription factors. [PDF]

J Biomol Screen, 2011
Bouck DC, Shu P, Cui J, Shelat A, Chen T.   +4 more
europepmc   +1 more source