Results 231 to 240 of about 94,681 (279)
Regulatory mechanism of O‐linked N‐acetylglucosamine protein modification on autophagy in cancer
O‐GlcNAcylation serves as a nutrient and stress sensor that dynamically regulates autophagy at multiple stages in cancer cells. It fine‐tunes autophagy initiation, maturation and fusion by modifying key proteins such as ULK1, ATG4B and SNAP‐29. Context‐dependent O‐GlcNAcylation promotes tumour adaptation and therapy resistance via autophagy remodelling.
Yizhan Li +5 more
wiley +1 more source
Forkhead transcription factors in chronic inflammation. [PDF]
Peng SL.
europepmc +1 more source
This figure summarises circRNAs identified as therapeutic or pathogenic targets in animal models of diabetic foot ulcers. Protective circRNAs delivered via exosomes, hypoxia‐preconditioned exosomes, or lipid nanoparticles promote angiogenesis, autophagy, and oxidative stress resistance. In contrast, silencing of pathogenic circRNAs such as circ_0005654
Amir Reza Ghafourian +6 more
wiley +1 more source
Forkhead transcription factors and cardiovascular biology. [PDF]
Papanicolaou KN, Izumiya Y, Walsh K.
europepmc +1 more source
This study investigates whether gestational probiotic and vitamin D supplementation can mitigate CPF effects in Wistar rats. While supplementation did not reverse CPF‐induced deficits, it induced notable neurodevelopmental changes in control animals, underscoring the need for further research on prenatal supplementation safety.
Mario Coca +8 more
wiley +1 more source
Role of transcription factor acetylation in the regulation of metabolic homeostasis [PDF]
core +1 more source
Forkhead box transcription factors in nutrient signaling
Margret Helene Agnes Johanna Luise BÃ ⁄ low
openalex +1 more source
The modified calycosin derivative H10 was more effective in inhibiting cell proliferation through G0/G1 cell cycle arrest, together with inhibiting the migration and colony formation abilities of ovarian cancer cell lines SKOV3 and A2780. Comparative proteomic analysis coupled with Ingenuity Pathway Analysis further delineated calycosin derivative H10 ...
Fuhong Yang +8 more
wiley +1 more source
Advantages and Possibility of Transcription Factors FOXOs in HCC. [PDF]
Xiufeng G, Zhiping H, Jingzhi W.
europepmc +1 more source
Lys–Leu MRPs heat‐treated for 2 h exhibited high antioxidant activity in vitro. A treatment with Lys–Leu MRPs extends the lifespan and health span of C. elegans by regulating ROS levels through their inherent antioxidant activity and the IIS pathway.
Yaqi Jia +4 more
wiley +1 more source

