Results 251 to 260 of about 626,933 (316)

T Cell Exhaustion in Hepatocellular Carcinoma: A Substantial Barrier in Immunotherapy

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Hepatocellular carcinoma (HCC), accounting for over 90% of primary liver cancers, remains a major global challenge for healthcare professionals. While immunotherapy has transformed the landscape of cancer treatment, its success is often limited by immune resistance, particularly through T cell exhaustion which remains a major barrier to ...
Kosar Nouri, Negar Asadollahei, Yasamin Haghir‐Sharif‐Zamini, Homeyra Seydi, Mahsa Salehi, Mehrnaz Mesdaghi, Mustapha Najimi, Massoud Vosough   +7 more
wiley   +1 more source

Persimmon carotenoid extract rich in β‐cryptoxanthin improves glucose homeostasis and reduces liver damage in high‐fat‐diet‐induced type 2 diabetic and metabolic dysfunction‐associated steatotic liver disease mice

Journal of the Science of Food and Agriculture, Volume 106, Issue 2, Page 1299-1313, 30 January 2026.
Abstract Background Persimmon (Diospyros kaki Thunb.) byproducts are a remarkable source of bioactive compounds, particularly carotenoids. Several studies suggest that carotenoids have beneficial effects in prevention of a large number of diseases. This study aims to highlight the effects of a persimmon carotenoid extract (PSCE) rich in β‐cryptoxanthin
Bryan Moreno‐Chamba, Nuria Martí, Antonio Cárdenas, María Soledad Fernández‐Pachón, Blanca Escudero‐López, Franz Martín, Julio Salazar‐Bermeo, Manuel Valero, Domingo Saura, María Concepción Martínez‐Madrid, Genoveva Berná   +10 more
wiley   +1 more source

MicroRNA-34a Perturbs B Lymphocyte Development by Repressing the Forkhead Box Transcription Factor Foxp1 [PDF]

, 2010
Dinesh S. Rao, Ryan M. O’Connell, Aadel A. Chaudhuri, Yvette Garcia-Flores, Theresa L. Geiger, David Baltimore   +5 more
openalex   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

International Journal of Cancer, Volume 158, Issue 2, Page 314-332, 15 January 2026.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano, Tina Keshavarzian, Nadine Biernath, Annika Fendler, Maria de Santis, Joachim Weischenfeldt, Mathieu Lupien   +6 more
wiley   +1 more source

FOXL2 mutations in Indian families with blepharophimosis-ptosis-epicanthus inversus syndrome [PDF]

, 2007
De Baere, Elfride, Jitendra, Jethani, Nallathambi, Jeyabalan, Neethirajan, Guruswamy, Sundaresan, Periasamy, Usha, Kim   +5 more
core   +2 more sources

Insulin‐like growth factor‐I–forkhead box O transcription factor 3a counteracts high glucose/tumor necrosis factor‐α‐mediated neuronal damage: Implications for human immunodeficiency virus encephalitis

, 2010
Anna Wilk, Katarzyna Urbańska, Shuo Yang, Jin Ying Wang, Shohreh Amini, Luis Del Valle, Francesca Peruzzi, Leonard G. Meggs, Krzysztof Reiss   +8 more
openalex   +2 more sources

Cell Cycle Inhibition by FoxO Forkhead Transcription Factors Involves Downregulation of Cyclin D

Molecular and Cellular Biology, 2002
Marc Schmidt, Sylvia Fernandez de Mattos, A. van der Horst, R. Klompmaker, G. Kops, E. Lam, B. Burgering, R. Medema   +7 more
semanticscholar   +1 more source

The forkhead transcription factor Foxi1 directly activates the AE4 promoter [PDF]

, 2005
Ingo Kurth, Moritz Hentschke, Suna Hentschke, Uwe Borgmeyer, Andreas Gal, Christian A. Hübner   +5 more
openalex   +1 more source

Inhibition of Phosphorylation of a Forkhead Transcription Factor Sensitizes Human Ovarian Cancer Cells to Cisplatin [PDF]

, 2004
Emi Arimoto‐Ishida, Masahide Ohmichi, Seiji Mabuchi, Toshifumi Takahashi, Chika Ohshima, Jun Hayakawa, Akiko Kimura, Kazuhiro Takahashi, Yukihiro Nishio, Masahiro Sakata, Hirohisa Kurachi, Keiichi Tasaka, Yuji Murata   +12 more
openalex   +1 more source

Foxj2 Attenuates LPS-Induced Inflammatory Response in Macrophages. [PDF]

Mediators Inflamm
Huang P, Fu J, Hu J, Lei Y, Dai C, Wu T, Liu J.   +6 more
europepmc   +1 more source