Results 61 to 70 of about 94,681 (279)

Identification of Melatonin-Regulated Genes in the Ovine Pituitary Pars Tuberalis, a Target Site for Seasonal Hormone Control [PDF]

, 2008
The pars tuberalis (PT) of the pituitary gland expresses a high density of melatonin (MEL) receptors and is believed to regulate seasonal physiology by decoding changes in nocturnal melatonin secretion.
Alison Downing, Ando, Andrew S. I. Loudon, Ashburner, Bae, Barrett, Bartness, Bechtold, Benoit Malpaux, Bockers, Bockers, Bockmann, Brahimi-Horn, Camon, Carr, Chemineau, Chen, Curlewis, Daphne Mouzaki, Dardente, Dave W. Burt, David Waddington, Draghici, Dupre, Fukuhara, Gerald A. Lincoln, Ghorbel, Graham, Grossmann, Hanon, Hazlerigg, Hazlerigg, Hazlerigg, Hogenesch, Hu, Hu, Johnston, Johnston, Johnston, Julian R. E. Davis, Kel, Kijas, Klosen, Ko, Lamolet, Lee, Lincoln, Lincoln, Lincoln, Lincoln, Malpaux, Merks, Messager, Michan, Morgan, Morgan, Mutoh, Nakao, Naya, Naya, Nilaweera, Oki, Poulin, Reick, Revollo, Richard Talbot, Roepke, Rutter, Samal, Sandrine M. Dupré, Schroeder, Segawa, Stehle, Stirland, Storey, Su, Tobler, Tournier, Wagner, Westfall, Williams, Wittkowski, Yang, Yokoyama   +83 more
core   +2 more sources

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

The relationship between the variants in the 5′-untranslated regions of equine chorionic gonadotropin genes and serum equine chorionic gonadotropin levels [PDF]

Asian-Australasian Journal of Animal Sciences, 2017
Objective An experiment was conducted to study the association between the single nucleotide polymorphisms (SNPs) in 5′-untranslated regions (5′-UTR) of equine chorionic gonadotropin (eCG) genes and the serum eCG levels.
ShuQin Liu, Song Lian, YunZhou Yang, ChunZheng Fu, HongYing Ma, ZhiYao Xiong, Yao Ling, ChunJiang Zhao   +7 more
doaj   +1 more source

Gene Structure, cDNA Sequence, and mRNA Distribution [PDF]

, 1994
The rat HNF-3 (hepatocyte nuclear factor 3) gene family encodes three transcription factors known to be important in the regulation of gene expression in liver and lung.
Hiemisch, Holger, Kaestner, Klaus H., Luckow, Bruno, Schütz, Günther   +3 more
core   +1 more source

Single‐Cell Transcriptome Atlas Reveals the Underlying Mechanism of Kynurenic Acid in the Regulation of Tumor Immune Microenvironment in Glioblastoma

Advanced Science, EarlyView.
KYNA regulates the tumor immune microenvironment in glioblastoma. KYNA reprograms the balance between T cell exhaustion and activation to suppress glioblastoma progression through inhibiting exhaustion‐associated markers (such as PD‐1, LAG3, and TOX) and enhancing immune activation and cytotoxicity markers including granzymes GZMA and GZMB.
Di Chen, Liming Sun, Jiajun Chen, Zi Ye, Xuqiang Zhu, Hongjiang Li, Lixin Wu, Guohua Zhao, Qinghao Zhang, Guangyi Jiang, Yuchen Ji, Yake Xue, Hongwei Li, Ruokun Chen, Hongwei Zheng, Rong Zeng, Dongming Yan, Yong Zhang, Xueyuan Li, Jing Yan   +19 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Notch and NF-kB: Coach and Players of Regulatory T-Cell Resposnse in Cancer [PDF]

, 2018
The Notch signaling pathway plays multiple roles in driving T-cell fate decisions, proliferation, and aberrant growth. NF-kB is a cell-context key player interconnected with Notch signaling either in physiological or in pathological conditions.
Bellavia, Diana, Campese, Antonio Francesco, Felli, MARIA PIA, Ferrandino, Francesca, Grazioli, Paola, Screpanti, Isabella   +5 more
core   +2 more sources

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

Transcriptional Regulation of Neuronal Genes and Its Effect on Neural Functions: NAD-Dependent Histone Deacetylase SIRT1 (Sir2α)

Journal of Pharmacological Sciences, 2005
Sir2 (silent information regulator 2) is an NAD-dependent deacetylase that is broadly conserved from bacteria to humans. It catalyzes a unique deacetylation reaction using NAD, and specific inhibitors and activators of its activity have been discovered ...
Shin Hisahara, Susumu Chiba, Hiroyuki Matsumoto, Yoshiyuki Horio   +3 more
doaj   +1 more source

Supplementary Data from Forkhead Transcription Factor FOXO1 is a Direct Target of Progestin to Inhibit Endometrial Epithelial Cell Growth [PDF]

, 2023
Satoru Kyo, Junko Sakaguchi, Tohru Kiyono, Yutaka Shimizu, Yoshiko Maida, Yasunari Mizumoto, Noriko Mori, Mitsuhiro Nakamura, Masahiro Takakura, Kiyohiko Miyake, Masaru Sakamoto, Masaki Inoue   +11 more
openalex   +1 more source