Results 71 to 80 of about 626,933 (316)

Acupuncture and cellular mechanisms: the role of foxo transcription factors in autophagy and senescence

Journal of the Pakistan Medical Association
The current narrative review was planned to elucidate the interplay between acupuncture, a cornerstone of Traditional Chinese Medicine, and the modulation of cellular mechanisms via Forkhead box O transcription factors, focussing on autophagy and ...
Lizhi Zhou, Xuying Li, Jinbi Ao, Na Duan
doaj   +1 more source

Transcriptional Regulation of Neuronal Genes and Its Effect on Neural Functions: Expression and Function of Forkhead Transcription Factors in Neurons

Journal of Pharmacological Sciences, 2005
Forkhead box transcription factor, class O (FOXO) is a mammalian homologue of DAF-16, which is known to regulate the lifespan of Caenorhabditis elegans and includes subfamilies of forkhead transcription factors such as AFX, FKHRL1, and FKHR.
Kohji Fukunaga, Takao Ishigami, Takayuki Kawano   +2 more
doaj   +1 more source

Quantitative model of eukaryotic Cdk control through the Forkhead CONTROLLER

npj Systems Biology and Applications, 2021
In budding yeast, synchronization of waves of mitotic cyclins that activate the Cdk1 kinase occur through Forkhead transcription factors. These molecules act as controllers of their sequential order and may account for the separation in time of ...
Matteo Barberis
doaj   +1 more source

Gene Structure, cDNA Sequence, and mRNA Distribution [PDF]

, 1994
The rat HNF-3 (hepatocyte nuclear factor 3) gene family encodes three transcription factors known to be important in the regulation of gene expression in liver and lung.
Hiemisch, Holger, Kaestner, Klaus H., Luckow, Bruno, Schütz, Günther   +3 more
core   +1 more source

FOXO transcription factors in antioxidant defense

IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2021
Forkhead box, class O (FOXO) family proteins are widely expressed and highly conserved transcriptional regulators that modulate cellular fuel metabolism, stress resistance and cell death.
Niklas Krafczyk, L. Klotz
semanticscholar   +1 more source

MS-Based Approaches Enable the Structural Characterization of Transcription Factor/DNA Response Element Complex

Biomolecules, 2019
The limited information available on the structure of complexes involving transcription factors and cognate DNA response elements represents a major obstacle in the quest to understand their mechanism of action at the molecular level.
Lukáš Slavata, Josef Chmelík, Daniel Kavan, Růžena Filandrová, Jan Fiala, Michal Rosůlek, Hynek Mrázek, Zdeněk Kukačka, Karel Vališ, Petr Man, Michael Miller, William McIntyre, Daniele Fabris, Petr Novák   +13 more
doaj   +1 more source

Identification of Melatonin-Regulated Genes in the Ovine Pituitary Pars Tuberalis, a Target Site for Seasonal Hormone Control [PDF]

, 2008
The pars tuberalis (PT) of the pituitary gland expresses a high density of melatonin (MEL) receptors and is believed to regulate seasonal physiology by decoding changes in nocturnal melatonin secretion.
Alison Downing, Ando, Andrew S. I. Loudon, Ashburner, Bae, Barrett, Bartness, Bechtold, Benoit Malpaux, Bockers, Bockers, Bockmann, Brahimi-Horn, Camon, Carr, Chemineau, Chen, Curlewis, Daphne Mouzaki, Dardente, Dave W. Burt, David Waddington, Draghici, Dupre, Fukuhara, Gerald A. Lincoln, Ghorbel, Graham, Grossmann, Hanon, Hazlerigg, Hazlerigg, Hazlerigg, Hogenesch, Hu, Hu, Johnston, Johnston, Johnston, Julian R. E. Davis, Kel, Kijas, Klosen, Ko, Lamolet, Lee, Lincoln, Lincoln, Lincoln, Lincoln, Malpaux, Merks, Messager, Michan, Morgan, Morgan, Mutoh, Nakao, Naya, Naya, Nilaweera, Oki, Poulin, Reick, Revollo, Richard Talbot, Roepke, Rutter, Samal, Sandrine M. Dupré, Schroeder, Segawa, Stehle, Stirland, Storey, Su, Tobler, Tournier, Wagner, Westfall, Williams, Wittkowski, Yang, Yokoyama   +83 more
core   +2 more sources

Targeting the core of neurodegeneration: FoxO, mTOR, and SIRT1

Neural Regeneration Research, 2021
The global increase in lifespan noted not only in developed nations, but also in large developing countries parallels an observed increase in a significant number of non-communicable diseases, most notable neurodegenerative disorders.
Kenneth Maiese
doaj   +1 more source

Forkhead transcription factors in the regulation of VEGF in breast cancer

, 2011
High levels of the major angiogenic factor VEGF, have been reported in a number of cancer cell lines and in clinical specimens derived from breast.
Karadedou, Christina Theano, Karadedou, Christina Theano   +1 more
core   +1 more source

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. [PDF]

, 2015
The current knowledge on how transcription factors (TFs), the ultimate targets and executors of cellular signalling pathways, are regulated by protein-protein interactions remains limited.
Anna Malovannaya, David H Hawke, Jiadong Wang, Jun Qin, Junjie Chen, Kaestner KH, Rudy Guerra, Wei Li, Wenqi Wang, Xu Li, Yuanxin Xi   +10 more
core   +2 more sources