Results 51 to 60 of about 442,575 (310)
The Journal of Quality in Education, 2021 La formation continue des enseignants au Maroc a pris des formes multiples et diversifiées sur le plan organisationnel et fonctionnel. Aussi le recours à la formation continue reste-t-il, malgré tout, faible et n’atteint généralement pas les résultats ...
Abdesselam MILI +2 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Revue Internationale de Pédagogie de l’Enseignement Supérieur, 2012 Aux prises avec des besoins particuliers de formation de leurs gestionnaires pour soutenir la gestion de leur autonomie gouvernementale, les communautés autochtones se tournent aujourd’hui vers les universités pour conclure des partenariats de formation.
Jean-François Savard
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Quels financements pour la formation professionnelle continue ?
Revue Internationale d’Éducation de Sèvres, 1999 In the perspective of lifelong training, vocational training and teaching are indispensable elements in a national economy. The question of funding is crucial to reply to an ever increasing demand.
Gregory Wurzburg
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The Journal of Quality in Education, 2018 L'amélioration de la gestion scolaire est devenue une nécessité dans les systêmes éducatifs vue les contraintes des changements actuels, c'est pourquoi le développement du rôle du directeur est placé en priorité et c'est ainsi qu'on mise actuellement sur
Kautara ELOMARI
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source