Results 61 to 70 of about 5,378,594 (299)

Formation continue en entreprise : faits et chiffres

open access: yes, 1999
Publ.
Commission européenne. Education formation jeunesse
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

[Negative impact of COVID-19 pandemic on peritonitis rate in peritoneal dialysis patients: Pleading for a continuous educational training]. [PDF]

open access: yesNephrol Ther, 2022
Jacobs L   +9 more
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Importance et difficulté de prendre en compte la mesure dans un système qualité universitaire

open access: yesThe Journal of Quality in Education, 2019
La maîtrise de la qualité de tout système passe par la maîtrise d'un processus de production de valeur, mais également - et on l'oublie trop souvent - par la maîtrise des processus de mesure.
MAURICE PILLET   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Dialectique entre architecture et peinture dans les archives : Le cas du palais Ahmed bey de Constantine (1826-1985)

open access: yesRevue d'Histoire Méditerranéenne
La production urbaine et architecturale de la période ottomane tardive en Algérie n’a suscité l’intérêt des scientifiques chercheurs qu’à partir de la fin des années 1990.
Makhoukh Nadia, Seffadj Zine Eddine
doaj  

Rapport des enseignant.e.s à la formation continue dans un contexte d’apprentissage tout au long de la vie (lifelong learning) [PDF]

open access: yes
Apparu dans les années 70, le concept de lifelong learning (LLL), après avoir été centré sur la formation continue comme phase distincte d’une formation initiale, est aujourd’hui plutôt compris comme un état d’esprit à la source d’actions d’apprentissage
Bonnat, Catherine, Paillard, Elodie
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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