Results 61 to 70 of about 442,575 (310)
, 2022 Cette recherche s’intéresse au développement de l’identité professionnelle de formateurs d’enseignants impliqués dans des formations continues certifiantes (ou diplômantes) d’enseignants de l’enseignement obligatoire ou post-obligatoire.
Sá, Silvia +3 more
core
L’enseignement technologique et professionnel français... et la formation tout au long de la vie
Revue Internationale d’Éducation de Sèvres, 1997 Étudiant les évolutions de la formation initiale et professionnelle d’une catégorie de la population, celle des ouvriers et employés, l’auteur démontre, preuves à l’appui, qu’il y a nécessité à reformuler les objectifs de la formation initiale et à ...
Benoît Bouyx
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Dossier "Formation et d'éducation continue" /
, 1989 (rel. à l'anglaise)Notes (part.
Société de formation et d'éducation continue
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Démarche partagée d'individualisation en formation initiale et continue
Revue Internationale d’Éducation de Sèvres, 1997 Les démarches d'individualisation sont un autre exemple de dispositif partagé : les formations générales et professionnelles, quelles soient initiales, différées, continues, tendent à échanger et adapter leurs procédures.
Michel Hauw, Guy Marchant
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source