Results 71 to 80 of about 436,799 (263)
A qualidade das definições normativas da educação à distância no ensino superior do Brasil
Revista Produção Online, 2003 The text presents in systematic way, in theoretical and reflective character, the qualilative and more excellent aspects, the one that exist in terms of norms and procedures, since the promulgation of the LDB nº 9.394 of 1996 until the moment, that the ...
Solange Coelho de Azevedo +1 more
doaj
Revue des Sciences de la SantéEn République Démocratique du Congo (RDC), malgré les initiatives mises en place pour améliorer l'accès aux soins palliatifs, les établissements médicaux se heurtent à un manque de personnel qualifié, à l'absence de programmes éducatifs systématiques et ...
Emilie MBOLO ZONGA +4 more
doaj +1 more source
La formation continue numérisée face à ses discontinuités
Lien Social et Politiques, 2018 Dans un contexte caractérisé par la volonté d’accroître la responsabilisation individuelle des salariés dans l’acquisition et le maintien de leurs compétences professionnelles, l’utilisation du numérique apparaît aux yeux de certains décideurs comme une ...
Anca Boboc, Jean-Luc Metzger
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Revue des Sciences de la SantéLe domaine de l'imagerie médicale subit une mutation technologique accélérée, caractérisée par l'intégration de l'intelligence artificielle, le déploiement de techniques d'imagerie de pointe ainsi que l'émergence de nouvelles exigences relatives à la ...
Madeleine KANTUMOBE ESHIBA +6 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source