Results 101 to 110 of about 357,623 (272)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Institutionalising formative assessment through school reform: when educational policy and teacher education are misaligned

open access: yesCogent Education
The interest in formative assessment, which is highly valued in current conceptualisations of teacher assessment literacy, has led to a renewed focus on initial teacher education (ITE) programmes, as well as on the assessment education domain.
Serafina Pastore
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Reflections on academics' assessment literacy

open access: yesLondon Review of Education, 2015
This small-scale, mixed-methods study aims to investigate academics' understanding of formative and summative assessment methods and how assessment literacy impacts on their teaching methods.
doaj   +2 more sources

Formatives Assessment

open access: yes, 2023
Formatives Assessment gilt als wesentlicher Indikator fu¨r Unterrichtsqualität und ist Teil einer lernförderlichen Beurteilungskultur. Das Konzept des formativen Assessments geht davon aus, dass Beurteilungen als Teil eines Lernprozesses verstanden werden, mit dem Ziel, diesen zu erfassen und zu fördern.
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Harnessing Large Language Models for Scalable and Effective Formative Assessment in Higher Education: A Review

open access: yesTrends in Higher Education
Formative assessment is an integral component of higher education, fostering student learning through feedback, reflection, and iterative improvement.
Charith Narreddy   +2 more
doaj   +1 more source

Formative and shared assessment in higher education. Clarifying concepts and proposing interventions from the formative and shared assessment network [PDF]

open access: yesPsychology, Society & Education, 2012
The purpose of this paper is threefold: (a)-making an introduction to the formative and shared assessment at Higher Education teaching and tracing its connections within the process of convergence towards the Higher Education European Area (HEEA), (b ...
Víctor Manuel López Pastor
doaj  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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