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The pros and cons of cytokines for fowl adenovirus serotype 4 infection

Archives of Virology, 2021
Hepatitis-hydropericardium syndrome (HHS), caused by fowl adenovirus serotype 4 (FAdV-4), has spread on chicken farms worldwide, causing huge economic losses. Currently, the exact mechanism of pathogenesis of FAdV-4 remains unknown. Despite the severe inflammatory damage observed in chickens infected with pathogenic FAdV-4, few studies have focused on ...
Baiyu Wang, Huifang Guo, Jun Zhao
openaire   +2 more sources

Pathogenicity of fowl adenovirus (FAdV) serotype 4 strain SDJN in Taizhou geese

Avian Pathology, 2019
Hydropericardium hepatitis syndrome (HHS) is a fatal disease in chickens, mainly caused by fowl adenovirus serotype 4 (FAdV-4). Since June 2015, HHS has appeared in many provinces in China. The disease has spread from broilers to laying hens, breeders and Cherry Valley ducks, seriously endangering the health of the poultry industry in China.
Youxiang Diao, Y Tang, Jingdong Hu
exaly   +3 more sources

Immunological and molecular comparison of fowl adenovirus serotypes 4 and 10

Archives of Virology, 1995
Some discussion has centered on whether fowl adenovirus (FAV) serotypes 4 and 10 are distinct serotypes or in fact should be reclassified as a single serotype. We have undertaken a detailed characterisation of representatives of both serotypes in order to determine if types 4 and 10 should be grouped together or retained as distinct serotypes ...
K, Erny, J, Pallister, M, Sheppard
openaire   +2 more sources

Pathogenicity of duck circovirus and fowl adenovirus serotype 4 co-infection in Cherry Valley ducks.

Veterinary Microbiology, 2023
Duck circovirus (DuCV) is one of the most prevalent infectious viruses in the duck industry in China. Although the clinical symptoms vary, it often causes immunosuppression in the host and leads to secondary infection with other pathogens.
Mingyue Shen   +11 more
semanticscholar   +1 more source

Fowl Adenovirus Serotype 4 Influences Arginine Metabolism to Benefit Replication

Avian Diseases, 2019
Hydropericardium syndrome (HPS) is caused by fowl adenovirus serotype 4 (FAdV-4). HPS has caused outbreaks in Chinese populations of broiler chickens since 2015. However, little is known about the molecular mechanisms underlying HPS. In this study, we used transcriptomic analysis to screen differentially expressed genes (DEGs) in the livers of FAdV-4 ...
Zhixin, Lin   +7 more
openaire   +2 more sources

Mechanism of fowl adenovirus serotype 4-induced heart damage and formation of pericardial effusion

open access: yesPoultry Science, 2019
Fowl adenovirus serotype 4 (FAdV-4) is the causative agent of hydropericardium syndrome (HPS), which is characterized by the accumulation of a clear, straw-colored fluid in the pericardial sac, and high mortality rates. In order to explore the mechanism of FAdV-4-induced cardiac damage, dynamic pathology, apoptosis, and inflammatory reactions were ...
Yujuan Niu, Xingpo Liu, Sidang Liu
exaly   +3 more sources

A self-assembled Fiber2 nanoparticle vaccine confers superior protection against fowl adenovirus serotype 4 infection.

International Journal of Biological Macromolecules
Since 2015, hepatitis-pericardial effusion syndrome caused by fowl adenovirus serotype 4 (FAdV-4) has resulted in serious economic losses to the poultry industry in China, highlighting the urgent need for safe and effective vaccines.
Xiaofeng Dong   +10 more
semanticscholar   +1 more source

Prevalence of Fowl Adenovirus Serotype 4 and Co-Infection by Immunosuppressive Viruses in Fowl with Hydropericardium Hepatitis Syndrome in Shandong Province, China

open access: yesViruses, 2019
Fowl adenovirus serotype 4 (FAdV-4) is the pathogenic agent of hydropericardium hepatitis syndrome (HHS) in chickens and ducks, which has caused huge economic losses for the Chinese poultry industry since 2015.
Guanliu Yu, Y Tang, Diao Youxiang
exaly   +2 more sources

Characterization of fowl adenovirus serotype-4 associated with hydropericardium syndrome in chicken

Comparative Immunology, Microbiology and Infectious Diseases, 2002
The polypeptides of three fowl adenovirus-4 (FAV-4) field isolates of hydropericardium syndrome from various geographical areas of the country and the standard FAV-1 (CELO virus) were subjected to sodium dodecyl sulfate polyacrylamide gel electrophoresis and analysed by protein immunoblotting with polyclonal antibodies to FAV-4 and FAV-1.
V, Balamurugan   +4 more
openaire   +2 more sources

Fowl adenovirus serotype 4 ORF1B protein suppresses type I interferon production by inhibiting IRF7 nuclear translocation.

Cytokine
Fowl adenovirus serotype 4 (FAdV-4), the causative agent of hepatitis-hydropericardium syndrome (HHS), has been reported to counter the host innate immune response. However, the underlying mechanisms employed by FAdV-4 to block cellular antiviral defense
Shenyan Gao   +6 more
semanticscholar   +1 more source

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