Results 151 to 160 of about 2,810 (168)

Virulence of fowl adenovirus (FAdV) serotype 4 strains impacts cell proliferation and immune response of primary chicken-embryo intestinal epithelial cells

Veterinary Research
Fowl adenovirus serotype 4 (FAdV-4) causes hepatitis-hydropericardium syndrome (HHS) in chickens, leading to substantial economic losses. Following oral uptake, the virus infects intestinal epithelial cells (IEC) to overcome the first entrance barrier ...
Katharina Kau-Strebinger, Ursula Reichart, T. Mitra, B. Grafl, Michael Hess, D. Liebhart   +5 more
semanticscholar   +1 more source

Fowl Adenovirus Serotype 4 Associated with Outbreaks of Infectious Hydropericardium in Haryana, India

Avian Diseases, 2002
During 1998, hydropericardium syndrome was observed among 3-to-6-wk-old broilers in 45 different flocks of Haryana, India, with mortality ranging between 10% and 30%. Fowl adenovirus (FAV) was isolated from one of the affected flocks by chicken embryo liver cell culture.
Swati, Dahiya, Ravinder N, Srivastava, Michael, Hess, Baldev R, Gulati   +3 more
openaire   +2 more sources

Genetic regulation of short chain fatty acid on Leghorn male hepatoma cells infected with Fowl Adenovirus serotype-4.

Veterinary Microbiology
Fowl Adenovirus serotype 4 (FAdV-4) infection causes hepatitis-hydropericardium syndrome (HHS), a disease with high mortality in poultry. Short chain fatty acids (SCFAs) are a major gut metabolite that strengthens barrier function, impacts microbiome ...
Rangyeon Lee, Hyunjin Song, Junghoon Kim, H. Sung, H. Kwon, Christopher A. Hunter, Jeongho Park   +6 more
semanticscholar   +1 more source

Identification of ORF1B as a unique nonstructural protein for fowl adenovirus serotype 4

Microbial Pathogenesis
Fowl adenovirus serotype 4 (FAdV-4), the causative agent of hepatitis-hydropericardium syndrome (HHS), is a double-stranded DNA virus. Although many structural proteins have been deeply studied, the coding potential of some other open reading frames (ORFs) and the biological functions of their products during virus infection have not been fully ...
Shenyan, Gao, Ruixue, Li, Xiaozhan, Zhang, Zeng, Wang   +3 more
openaire   +2 more sources

Fowl adenovirus serotype 4-induced apoptosis, autophagy, and a severe inflammatory response in liver

Veterinary Microbiology, 2018
Fowl adenovirus serotype 4 (FAdV-4) is a hepatotrophic virus that causes severe liver diseases. Upon histological examination, the most remarkable findings in the liver are small multifocal areas of necrosis and mononuclear cell infiltration, including basophilic intranuclear inclusion bodies in hepatocytes surrounded by a clear halo or which fill the ...
Yujuan, Niu, Qinqin, Sun, Guihua, Zhang, Xingpo, Liu, Yingli, Shang, Yihong, Xiao, Sidang, Liu   +6 more
openaire   +2 more sources

Fowl adenovirus serotype 4 (FAdV-4) infection induces inflammatory responses in chicken embryonic cardiac fibroblasts via PI3K/Akt and IκBα/NF-κB signaling pathways.

Research in Veterinary Science
Fowl adenovirus serotype 4 (FAdV-4) is the main pathogen of the acute infectious disease hepatitis-hydropericardium syndrome (HHS). Previous studies have focused on the mechanisms of FAdV-4 caused liver injury, while studies revealing potential ...
Xiao Feng, Dejing Yin, Tian Fang, C. Zhao, Jun Yue, Erpeng Zhu, Zhentao Cheng   +6 more
semanticscholar   +1 more source

Evaluation of a Bivalent Hexon-L1 and Fiber-2 Subunit Vaccine Candidate Against Homologous Fowl Adenovirus Serotype 4 Challenge in Chickens

Microbiology Research
Fowl adenovirus serotype 4 (FAdV-4) is the major causative agent of hydropericardium-hepatitis syndrome (HHS), a disease responsible for considerable economic losses in poultry production.
Xiaoran Chu, Kailin Wang, Vincenzo Cuteri, Cheng Liu, Yubao Li, Zhenshu Si   +5 more
semanticscholar   +1 more source

HSP90α promotes fowl adenovirus serotype 4 replication in LMH cells via interacting with hexon

Avian Pathology
Heat shock protein 90 alpha (HSP90α), a conservative chaperone protein, is closely involved in signal transduction and virus proliferation, but how it engages the lifecycle of fowl adenovirus serotype 4 (FAdV-4) remains unknown.
Saimin Zhai, Xiaozhan Zhang, Keying Liu, Huichao Gao, Linyang Yu, Jianli Li, Xia Yang, Jun Zhao, Zeng Wang   +8 more
semanticscholar   +1 more source

Establishment of an RAA-CRISPR/Cas12a-based diagnostic method for the detection of fowl adenovirus serotype 4 virus in chickens and wild birds

Animal Diseases
Xinhua Zhang, Yulin Zhan, Hao Wu, Ping Zhou, Yumei Fu, Lun Yao, Duo Fang   +6 more
semanticscholar   +1 more source

Development of colloidal gold-based test strip for rapid detection of serotype 4 fowl adenovirus

Journal of Virological Methods, 2021
Quan Xie, Tuofan Li, Zhimin Wan
exaly