Results 221 to 230 of about 167,256 (310)

CD38 endows local antigen-specific T_reg cells with stress resilience for control of compartmentalized CNS inflammation. [PDF]

Nat Immunol
Chen HH, Tyystjärvi S, Ruiz Navarro D, Kant R, Groll T, Wagner I, Domínguez Moreno H, Bonafonte-Pardàs I, Öllinger R, Afzali AM, Heink S, Richter LC, Sie C, Lepennetier G, Seeholzer L, Steiger K, Merkler D, Rad R, Schotta G, Schubert B, Muschaweckh A, Korn T.   +21 more
europepmc   +1 more source

CCR8 orchestrates an immunosuppressive niche in the liver to promote Echinococcus multilocularis infection. [PDF]

PLoS Negl Trop Dis
Hou J, Fan H.
europepmc   +1 more source

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

iMetaMed, EarlyView.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang, Ke Zhang, Lijie Xia, Jinyao Li   +3 more
wiley   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Delineating phenotypic heterogeneity in human regulatory T cells across developmental stages and therapeutic sources. [PDF]

Front Immunol
Santosh Nirmala S, Hu Y, Floegel FD, Cruz H, Morgenstern J, Platz A, Vollroth M, Fuchs A.   +7 more
europepmc   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source

The role of miRNAs in the development of Super-Tregs as a potential therapy for neurodegenerative diseases. [PDF]

Front Immunol
Mukherjee K, Bhattacharyya SN.
europepmc   +1 more source

Monocytes with trained immunity–like signatures are associated with acute anterior uveitis in ankylosing spondylitis

Interdisciplinary Medicine, EarlyView.
In ankylosing spondylitis‐acute anterior uveitis (AS‐AAU), trained immunity monocytes (Mono‐TI) differentiate into macrophages in the eye, retaining trained immunity features. Mono‐TI cells secrete pro‐inflammatory cytokines and chemokines, including IL‐1β, TNF‐α, and CCL3.
Yimeng Sun, Lu Zhang, Xinyu Yao, Yunfei Liu, Xin Li, Feng Wen, Yong Dai, Ye Dai, Ziyu Du, Dijie Qiao, Ziwei Meng, Cong Hu, Chun Yan, Wei Chi   +13 more
wiley   +1 more source

Distribution and prognostic value of T-cells in primary colorectal cancer and adjacent non-tumor mucosa in stage IV versus stage I-III patients. [PDF]

Int J Cancer
Ali E, Ye W, Pavlov S, Červenková L, Ambrozkiewicz F, Vyčítal O, Hošek P, Daum O, Liška V, Hemminki K, Trailin A.   +10 more
europepmc   +1 more source