Results 251 to 260 of about 199,492 (387)

Tumor infiltrating Foxp3⁺ regulatory T‐cells are associated with recurrence in pathologic stage I NSCLC patients [PDF]

, 2006
Rebecca P. Petersen, Michael J. Campa, Justin Sperlazza, Debbi H. Conlon, M. Joshi, David H. Harpole, Edward F. Patz   +6 more
openalex   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Interferon Regulatory Factor 4 dose-dependently controls peripheral Treg cell differentiation and homeostasis by modulating chromatin accessibility in mice. [PDF]

Front Immunol
Voß LC, Schmidt C, Harberts A, Spohn M, Bradtke P, Borchers A, Fertig S, Schmid J, Koch-Nolte F, Krebs CF, Raczkowski F, Mittrücker HW.   +11 more
europepmc   +1 more source

Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens [PDF]

, 2006
Isabelle Suffia, Stacie Reckling, Ciriaco A. Piccirillo, Romina S. Goldszmid, Yasmine Belkaid   +4 more
openalex   +1 more source

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

Immunomodulatory mechanisms of the gut microbiota and metabolites on regulatory T cells in rheumatoid arthritis. [PDF]

Front Immunol
Xu X, Zhou J, Xie H, Zhang R, Gu B, Liu L, Liu M, Chang X.   +7 more
europepmc   +1 more source

Role of IFN-g in induction of Foxp3 and conversion of CD4+CD25- T cells to CD4+ Tregs [PDF]

, 2006
Zhaojun Wang
openalex   +1 more source

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

Cancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai, Tao Fan, Chu Xiao, Ziqin Deng, Yixiao Liu, Chunxiang Li, Jie He   +6 more
wiley   +1 more source

Estrogen protects against postpartum Concanavalin A-induced hepatitis by promoting intrahepatic CD4⁺CD25⁺ Treg expansion through activation of the PI3K/Akt signaling pathway in HBV-Tg mice. [PDF]

Virol J
Xu C, Su Y, Lu W, Dong J, Wang L, Mi Y, Jia X, Lv W, Wu S, Jia Y, Ying H.   +10 more
europepmc   +1 more source

Foxp3+CD25+CD4+ natural regulatory T cells in dominant self‐tolerance and autoimmune disease

Immunological Reviews, 2006
S. Sakaguchi, M. Ono, Ruka Setoguchi, H. Yagi, S. Hori, Z. Fehérvári, J. Shimizu, Takeshi Takahashi, T. Nomura   +8 more
semanticscholar   +1 more source