Results 251 to 260 of about 160,147 (340)
IGF2‐Reprogrammed Macrophages Ameliorate the Inflammatory Response and Protect Against the Neuroinflammatory Process in Parkinson's Disease Models
Aging Cell, EarlyView.Therapeutic Effects of IGF2‐Reprogrammed Macrophages (MIGF2) in Parkinson's Disease Progression in ASO Mice: This graphical abstract illustrates the therapeutic potential of IGF2‐reprogrammed macrophages (MIGF2) in mitigating Parkinson's disease progression in ASO mice.Felipe Grunenwald, Tomas J. Huerta, Denisse Sepulveda, Carolina Jerez, Valentina Urbina, Bárbara Carrera, Rodrigo Diaz‐Espinoza, Esteban Nova, Rodrigo Pacheco, Elisa Martín‐Montañez, Sara Gil‐Rodriguez, Nadia Valverde, María Garcia‐Fernandez, Carlos Aguilera, Pedro Chana‐Cuevas, René L. Vidal +15 morewiley +1 more sourceAZD8701, an Antisense Oligonucleotide Targeting FOXP3 mRNA, as Monotherapy and in Combination with Durvalumab: A Phase I Trial in Patients with Advanced Solid Tumors. [PDF]
Clin Cancer ResSiu LL, Postel-Vinay S, Villanueva-Vázquez R, de Velasco G, Castanon Alvarez E, Kyriakopoulos CE, Johnson M, Ouali K, McMorn S, Angell HK, Ng F, Saran S, Bayat M, Collins T, Roy A, Lambert AW, Cho S, Miller N, Petruzzelli M, Stone J, Massard C. +20 moreeuropepmc +1 more sourceStructure of the forkhead domain of FOXP2 bound to DNA [PDF]
, 2006 Bates, D., Chen, L., Han, A., Nowick, K., Pääbo, S., Stroud, J., Tong, H., Wu, Y. +7 morecore +2 more sourcesDeciphering Novel Communication Patterns in T Regulatory Cells From Very Old Adults
Aging Cell, EarlyView.Graphical summary depicting the changes in the co‐receptor landscape (a), migratory potential (b), differentiation program (c) and communication networks (d) in Tregs from the ‐< 66‐year‐old cohort versus the 85‐year‐olds. ABSTRACT
Regulatory T cells (Tregs) are important in maintaining tolerance and are key players in immunity.Tegan McTaggart, Jing Xuan Lim, Katie J. Smith, Bronagh Heaney, David McDonald, Gillian Hulme, Rafiqul Hussain, Jonathan Coxhead, Derek A. Mann, Avan A. Sayer, Antoneta Granic, Shoba Amarnath +11 morewiley +1 more sourceTargeting Setdb1 in T cells induces transplant tolerance without compromising antitumor immunity. [PDF]
Nat CommunTan X, Zhao X, Hu Z, Jiang DS, Ma Z, Sun L, Wang J, Huang X, Xie B, Wu M, Ma M, Wang CY, Zhang S, Chen L, Chen Z, Chen G, Lan P. +16 moreeuropepmc +1 more sourceImmunosenescence Profile Is Associated With Increased Susceptibility to Severe COVID‐19
Aging Cell, EarlyView.(A) A previous immunosenescence profile in individuals infected with SARS‐CoV2 creates a permissive environment for progression to severe COVID‐19: higher inflammaging, accumulation of exhausted/senescent T cells, an oligoclonal B‐cell repertoire, and accelerated epigenetic age.Lucas Haniel A. Ventura, Lícia Torres, Giovanna Caliman Camatta, Jofer Zamame, Monique Macedo Coelho, Cecília Horta Ramalho‐Pinto, João Gervazio, Felipe Caixeta, Leandro Nascimento, Mariana Almeida Oliveira, Vinícius Dantas Martins, Marcos Felipe Oliveira, Murilo Soares Costa, Hugo Itaru Sato, Henrique Cerqueira Guimarães, Rafael Calvão Barbuto, Ana Paula Rocha Veiga, Najara Ataíde, Gabriela Prandi Caetano, Sarah Rangon, Mauro Lúcio O. Júnior, Fernanda Calvo Fortes, Luciana Zuccherato, Elaine Speziali, Olindo Assis Martins‐Filho, Verônica Coelho, Roberto Avritchir, Rafael Souza, Marina Ayupe, Caio Loureiro, Maria Eduarda Passos, Ana Clara Mota Neves, Pauline Leite, Santuza Maria Ribeiro Teixeira, Unaí Tupinambás, Liza Figueiredo Felicori, Gabriela Silveira‐Nunes, Tatiani Uceli Maioli, Denise Morais Fonseca, Andrea Teixeira‐Carvalho, Ana Maria Caetano Faria +40 morewiley +1 more sourceFoxp3-Transduced Polyclonal Regulatory T Cells Protect against Chronic Renal Injury from Adriamycin
, 2006 Yuan Min Wang, Geoff Yu Zhang, Yiping Wang, Min Hu, Huiling Wu, Debbie Watson, Shohei Hori, Ian E. Alexander, David C.H. Harris, Stephen I. Alexander +9 moreopenalex +1 more sourceExtracorporeal Photopheresis Enhances the Frequency and Function of Highly Suppressive FoxP3 + Treg Subsets in Heart Transplanted Individuals. [PDF]
TransplantationMottola M, Bruzzaniti S, Piemonte E, Lepore MT, Petraio A, Romano R, Castiglione A, Izzo L, Perna F, De Falco C, Brighel F, Formisano L, Gravina MT, Marino M, De Feo M, Matarese G, Galgani M. +16 moreeuropepmc +1 more source