Results 81 to 90 of about 4,329 (161)

FPR1 affects acute rejection in kidney transplantation by regulating iron metabolism in neutrophils

open access: yesMolecular Medicine
Background Acute rejection (AR) is one of the significant factors contributing to poor prognosis in patients following kidney transplantation. Neutrophils are the main cause of early host-induced tissue injury.
Peiyuan Li   +8 more
doaj   +1 more source

Gliadin Induces Neutrophil Migration via Engagement of the Formyl Peptide Receptor, FPR1

open access: yesPLOS ONE, 2015
Gliadin, the immunogenic component within gluten and trigger of celiac disease, is known to induce the production of Interleukin-8, a potent neutrophil-activating and chemoattractant chemokine. We sought to study the involvement of neutrophils in the early immunological changes following gliadin exposure.Utilizing immunofluorescence microscopy and flow
Lammers K. M.   +9 more
openaire   +6 more sources

FPR1, as a Potential Biomarker of Diagnosis and Infliximab Therapy Responses for Crohn’s Disease, is Related to Disease Activity, Inflammation and Macrophage Polarization

open access: yesJournal of Inflammation Research
Chenglin Ye,1,* Sizhe Zhu,2,* Jingping Yuan,1 Xiuxue Yuan3 1Department of Pathology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China; 2Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji ...
Ye C, Zhu S, Yuan J, Yuan X
doaj  

Differential gene expression and miRNA regulatory network in coronary slow flow

open access: yesScientific Reports
Coronary slow flow (CSF) is characterized by slow progression of coronary angiography without epicardial stenosis. The aim of this study was to explore the potential biomarkers and regulatory mechanism for CSF.
Lihua Sun   +6 more
doaj   +1 more source

Exosomal secreted SCIMP regulates communication between macrophages and neutrophils in pneumonia

open access: yesNature Communications
In pneumonia, the deficient or delayed pathogen clearance can lead to pathogen proliferation and subsequent overactive immune responses, inducing acute lung injury (ALI).
Xiaolei Pei   +17 more
doaj   +1 more source

Formyl peptide receptor 1 (FPR1) [PDF]

open access: yesScience-Business eXchange, 2013
openaire   +1 more source

FPR1 is activated in the blood of humans with high CRP.

open access: yes
We measured total transcription in the blood in humans with low CRP and in humans with high CRP to identify causative factors in cardiovascular disease mediated by inflammation. We describe here activation of FPR1 in humans with high CRP.    
openaire   +1 more source

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