Results 91 to 100 of about 7,556 (242)

Identification of a novel mechanism of action of bovine IgG antibodies specific for Staphylococcus aureus

open access: yesVeterinary Research, 2018
Staphylococcus aureus is a major pathogen that causes subclinical mastitis associated with huge economic losses to the dairy industry. A few vaccines for bovine mastitis are available, and they are expected to induce the production of S.
Mutsumi Furukawa   +15 more
doaj   +1 more source

Ask a pathologist [PDF]

open access: yes, 2017
Question and answer regarding a patient who became acutely thrombocytopenic.Includes bibliographical ...
Coberly, Emily, Scheitler, Kristen
core  

Fc Engineering for Developing Therapeutic Bispecific Antibodies and Novel Scaffolds [PDF]

open access: yes, 2017
Therapeutic monoclonal antibodies have become molecules of choice to treat autoimmune disorders, inflammatory diseases, and cancer. Moreover, bispecific/multispecific antibodies that target more than one antigen or epitope on a target cell or recruit ...
Abhishek Saxena   +3 more
core   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

open access: yesAdvanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding   +5 more
wiley   +1 more source

Hepatotoxicity Associated with the Use of Anti-TNF-α Agents [PDF]

open access: yes, 2015
Medications to inhibit the actions of tumour necrosis factor alpha have revolutionized the treatment of several pro-inflammatory autoimmune conditions.
Bonacini, Maurizio   +4 more
core   +2 more sources

Designing Physical Unclonable Functions From Optically Active Materials

open access: yesAdvanced Materials, EarlyView.
Assigning unforgeable “fingerprints” to manufactured goods is a key strategy to fight global counterfeiting. Optical physical unclonable functions (PUFs) are chemically generated random patterns of optically active materials serving as unique authenticators.
Maxime Klausen   +2 more
wiley   +1 more source

Neospora caninum as delivery vehicle for anti-PD-L1 scFv-Fc: A novel approach for cancer immunotherapy

open access: yesMolecular Therapy: Oncology
Neospora caninum, a potential anticancer agent able to reactivate the immune response within the tumor microenvironment (TME), has recently shown enhanced immunomodulatory properties in different tumor models when armed with the cytokine, Il-15.
Clément Riviere   +11 more
doaj  

Quality, Non-clinical and Clinical Considerations for Biosimilar Monoclonal Antibody Development: EU, WHO, USA, Canada, and BRICS-TM Regulatory Guidelines [PDF]

open access: yes, 2018
Objective: The aim was to critically evaluate well-established regulatory agencies mAb biosimilar guidelines for development and marketing authorization about quality, efficacy and safety and compare to BRICS-TM regulations to identify challenges ...
Anvisa   +20 more
core   +4 more sources

Spatially Resolved Observation of Ferroelectric‐to‐Paraelectric Phase Transition in a Two‐Dimensional Halide Perovskite

open access: yesAdvanced Materials, EarlyView.
Temperature‐dependent nanoscale ferroelectric domain evolution and the ferroelectric‐to‐paraelectric phase transition in 2D halide perovskites is visualized using piezoresponse force microscopy. The phase transition initiates locally below the Curie temperature and progressively propagates as paraelectric regions expand.
Tae Hyun Jung   +14 more
wiley   +1 more source

The N-Glycosylation of Mouse Immunoglobulin G (IgG)-Fragment Crystallizable Differs Between IgG Subclasses and Strains

open access: yesFrontiers in Immunology, 2017
N-linked glycosylation of the fragment crystallizable (Fc)-region of immunoglobulin G (IgG) is known to have a large influence on the activity of the antibody, an effect reported to be IgG subclass specific. This situation applies both to humans and mice.
Noortje de Haan   +5 more
doaj   +1 more source

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