Results 81 to 90 of about 886 (145)

Advances of nanopore direct sequencing technology and bioinformatics analysis for cell-free DNA detection and its clinical applications in cancer liquid biopsy

Frontiers in Molecular Biosciences
Cell-free DNA (cfDNA) containing cancer information has become a key biomarker for cancer liquid biopsy. Current next-generation sequencing (NGS) technology for cfDNA detection often fail to capture multiomics information, such as fragmentomics ...
Jiaxin Tan, Jiaxin Tan, Zetong Wu, Yunya Zhu, Biyuan Miao, Biyuan Miao, Daofeng Xu, Jia Gu, Maohong Hu, Pingping Xu, Shaogui Wan   +10 more
doaj   +1 more source

The Method of Minimal Residual Disease Detection With Circulating Tumor DNA and Its Clinical Applications in Colorectal Cancer

Cancer Reports
Background Colorectal cancer (CRC) remains a significant health concern in the world. The existing standard of care guidelines for CRC surveillance fall short of effectively and timely detecting recurrence or metastasis.
Ming Liu, Tianhao Mu, Jia Gu, Mingyan Xu, Shifu Chen   +4 more
doaj   +1 more source

Author Correction: Quantitative fragmentomics allow affinity mapping of interactomes

Nature Communications, 2022
Gergo Gogl, Boglarka Zambo, Camille Kostmann, Alexandra Cousido-Siah, Bastien Morlet, Fabien Durbesson, Luc Negroni, Pascal Eberling, Pau Jané, Yves Nominé, Andras Zeke, Søren Østergaard, Élodie Monsellier, Renaud Vincentelli, Gilles Travé   +14 more
doaj   +1 more source

fRagmentomics: an R package for integrating cell-free DNA fragment features with mutational status to support liquid biopsy interpretation. [PDF]

Bioinformatics
Maudet K, Samaniego J, Pradat Y, Bernard E.   +3 more
europepmc   +1 more source

From concept to clinic: emerging paradigms and novel insights into liquid biopsy. [PDF]

Cancer Biol Med
Guo W, Liu Y, Dong H, Li X, Guo X, Guo H, Zhou K, Xing J.   +7 more
europepmc   +1 more source

Emerging Role of ctDNA Fragmentomics and Epigenetic Signatures in the Early Detection, Minimal Residual Disease Assessment, and Precision Monitoring of Renal Cell Carcinoma. [PDF]

J Cell Mol Med
Kamli H, Khan NU.
europepmc   +1 more source

Sinteza nove piridinijeve soli s triazolilidenskim fragmentom

, 2020
This thesis describes the synthesis of a novel pyridinium salt bearing triazolylidene fragment bounded to pyridine nitrogen atom, which has not yet been described in the literature. The synthesized salt represents a potential bidentate dicarbene NHC ligand, useful for the formation of transition metal NHC complexes.
openaire   +1 more source

Circulating cell-free mtDNA fragmentomics for early detection of gastric cancer and precancerous lesions. [PDF]

Cell Rep Med
Dang M, Wang S, Zhang H, Xu H, Lu L, Liu Y, Jiao H, Yang W, Peng F, Gao X, Lin F, Dong K, Pan K, Li W, Lu R, Nie Y, Liu Y, Xing J.   +17 more
europepmc   +1 more source

A machine learning framework combining cfDNA fragmentomics and serum biomarkers for early ovarian cancer detection. [PDF]

Cell Commun Signal
Weng W, Rao Q, Wang S, Lei R, Li R, Lin L, Liu Y, Zhu D, Bao H, Zhang W, Wei J, Qing X, Ruan X, Xu G, Zhang B.   +14 more
europepmc   +1 more source

Holistic determination of ends of cfDNA molecules. [PDF]

Cell Genom
Jiang P, Ma ML, Qiao R, Shi Y, Liu J, Zhou Q, Peng W, Lam WKJ, Bai J, Choy LYL, Tsui WHA, Malki Y, Kang G, Yu SCY, Xiong D, Wong GLH, Chan LL, Wong J, Chan SL, Wong VWS, Chan KCA, Lo YMD.   +21 more
europepmc   +1 more source