Results 71 to 80 of about 1,072 (154)

Cell-Free DNA Fragmentomics: The New “Omics” on the Block [PDF]

Clinical Chemistry, 2020
Rossa W K Chiu, Ellen Heitzer, Y M Dennis Lo, Florent Mouliere, Dana W Y Tsui   +4 more
openaire   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology
Liquid biopsies containing circulating tumor DNA (ctDNA) are important biomarkers across several forms of cancer. The detection of mutations in cell‐free DNA (cfDNA) indicates the presence of ctDNA.
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
doaj   +1 more source

Liquid Biopsy in Early Screening of Cancers: Emerging Technologies and New Prospects

Biomedicines
Liquid biopsy is moving beyond mutation-centric assays to multimodal frameworks that integrate cell-free DNA (cfDNA) signals with additional analytes such as circulating tumor cells (CTCs) and extracellular vesicles (EVs).
Hanyu Zhu, Zhenyu Li, Kunxin Xie, Sajjaad Hassan Kassim, Cheng Cao, Keyu Huang, Zipeng Lu, Chenshan Ma, Ying Li, Kuirong Jiang, Lingdi Yin   +10 more
doaj   +1 more source

Liquid biopsy in genitourinary oncology: From molecular detection to longitudinal precision cancer care

UroPrecision, Volume 4, Issue 3, Page 133-136, September 2026.
Shidong Jia, Liang Cheng
wiley   +1 more source

Leveraging cfDNA fragmentomic features for the early detection of colorectal cancer

Frontiers in Immunology
Background Early detection of colorectal cancer (CRC) is crucial for improving patient outcomes. Cell-free DNA (cfDNA) analysis has emerged as a promising non-invasive approach for cancer detection. This study aims to develop a machine learning algorithm leveraging cfDNA fragmentomic features to accurately ...
Shan, Lina, Xu, Dengyong, Chen, Jie, Liu, Wenjia, Lin, Ji, Bao, Juhang, Huang, Jianfei, Zhang, Hanqing, Zhao, Hanchen, Xue, Wei, Lin, Ziao, Bai, Bingjun   +11 more
openaire   +2 more sources

Macromolecular Fragmentation on the Skin Surface: Formation Mechanisms, Evidence Limitations, and Potential Relevance for Skin Homeostasis

Cosmetics
The skin surface is a dynamic biochemical interface where proteins, polysaccharides, lipids, and microbial or environmental molecules are continuously exposed to ultraviolet(UV) radiation, oxidative stress, mechanical stimulation, pH variation, host ...
Keran Jia, Xiao Ning, Liya Song, Jin Cao
doaj   +1 more source

Cancer treatment monitoring using cell-free DNA fragmentomes

Nature Communications
AbstractCirculating cell-free DNA (cfDNA) assays for monitoring individuals with cancer typically rely on prior identification of tumor-specific mutations. Here, we develop a tumor-independent and mutation-independent approach (DELFI-tumor fraction, DELFI-TF) using low-coverage whole genome sequencing to determine the cfDNA tumor fraction and validate ...
Iris van ’t Erve, Bahar Alipanahi, Keith Lumbard, Zachary L. Skidmore, Lorenzo Rinaldi, Laurel K. Millberg, Jacob Carey, Bryan Chesnick, Stephen Cristiano, Carter Portwood, Tony Wu, Erica Peters, Karen Bolhuis, Cornelis J. A. Punt, Jennifer Tom, Peter B. Bach, Nicholas C. Dracopoli, Gerrit A. Meijer, Robert B. Scharpf, Victor E. Velculescu, Remond J. A. Fijneman, Alessandro Leal   +21 more
openaire   +3 more sources

Comprehensive fragmentation of cell-free repetitive DNA for enhanced cancer detection in plasma

Frontiers in Cell and Developmental Biology
BackgroundRepetitive elements account for a large proportion of the human genome and undergo alterations during early tumorigenesis. However, the exclusive fragmentation pattern of DNA-derived cell-free repetitive elements (cfREs) remains unclear ...
Mingguang Zhang, Shuohui Dong, Wei Rao, Shiwen Mei, Gang Hu, Ling Liu, Zhen Wang, Jianqiang Tang   +7 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Abstracts of 14th International Symposium on Hodgkin Lymphoma

HemaSphere, Volume 10, Issue S2, October 2026.
wiley   +1 more source