Results 81 to 90 of about 1,208 (179)

Watch and Wait Strategy for Locally Advanced Rectal Cancer: Update From Results of Recent Clinical Trials

Cancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Locally advanced rectal cancer (LARC) is a common malignant tumor in the digestive system. Currently, despite growing recognition of personalized medicine, systematic risk stratification and full incorporation of patient preferences for anal preservation and treatment tolerance remain challenging in some clinical settings.
Ruocheng Yin, Zhigang Chen, Xinliang Liu, Dan Zong, Xia He   +4 more
wiley   +1 more source

Access to diagnosis using liquid biopsy (ADLiB): Identifying lymphoma in a tuberculosis‐endemic setting

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract In HIV‐ and tuberculosis (TB)‐endemic regions, lymphoma diagnosis is often delayed because symptoms can overlap with TB, and access to biopsy and specialized pathology is limited. To address this, we developed and internally evaluated the Access to Diagnosis using Liquid Biopsy (ADLiB) platform—a plasma cell‐free DNA (cfDNA)‐based approach ...
Katherine Antel, Nina Xiong, Mwanasha Merrill, Taiyang Chen, Lauren McGrath, Clara Droessler, Maxine van der Schyff, Meng‐Xuan Wu, Dylan Cheddie, Charlotte Slome, Liam McBride, Jonathan Day, Zainab Mohamed, Nazia Fakie, Nomonde Mbatani, Charlotte Shultz, Graeme Meintjes, Svitlana Tyekucheva, Elizabeth F. Cohen, Michael Y. Tolstorukov, Estelle Verburgh, Mark A. Murakami   +21 more
wiley   +1 more source

Liquid biopsy in genitourinary oncology: From molecular detection to longitudinal precision cancer care

UroPrecision, Volume 4, Issue 3, Page 133-136, September 2026.
Shidong Jia, Liang Cheng
wiley   +1 more source

Liquid Biopsy in Early Screening of Cancers: Emerging Technologies and New Prospects

Biomedicines
Liquid biopsy is moving beyond mutation-centric assays to multimodal frameworks that integrate cell-free DNA (cfDNA) signals with additional analytes such as circulating tumor cells (CTCs) and extracellular vesicles (EVs).
Hanyu Zhu, Zhenyu Li, Kunxin Xie, Sajjaad Hassan Kassim, Cheng Cao, Keyu Huang, Zipeng Lu, Chenshan Ma, Ying Li, Kuirong Jiang, Lingdi Yin   +10 more
doaj   +1 more source

Post‐surgery level of circulating DNA in stage III colon cancer patients: Impact on the reliability of minimal residual disease detection

International Journal of Cancer, Volume 158, Issue 10, Page 2771-2783, 15 May 2026.
What's New? Circulating nuclear DNA (cir‐nDNA)‐based assessment of minimal residual disease (MRD) offers powerful post‐surgery prognostic insight for stage III colon cancer (CC). Sparse knowledge of post‐surgical variations and origins in cir‐nDNA, however, has limited its clinical application.
Andrei Kudriavtsev, Saidi Daoud, Catalina Isabel Cofre Muñoz, Alexia Mirandola, Ekaterina Pisareva, Javier Gonzalo Ruiz, Marco Macagno, Nadia Saoudi Gonzalez, Evelyne Crapez, Marc Ychou, Ramon Salazar Soler, Elisabetta Fenocchio, Paula X. Fernandez Calotti, Thibault Mazard, Cristina Santos Vivas, Elena Elez, Federica Di Nicolantonio, Alain R. Thierry   +17 more
wiley   +1 more source

Liquid biopsy biomarkers for early detection of gastrointestinal cancers: Current landscape and emerging technologies

Clinical and Translational Medicine
Early detection of gastrointestinal (GI) cancers remains a critical unmet clinical need, as most patients are diagnosed at advanced stages when prognosis is poor.
Muhammad Anees, Christopher Sherry, Hyun Y. Park, Erin E. Grayhack, Arul Goel, Alisha F. Khan, Ashten Omstead, David L. Bartlett, Ajay Goel, Neda Dadgar, Patrick L. Wagner, Ali H. Zaidi   +11 more
doaj   +1 more source

Leveraging cfDNA fragmentomic features for the early detection of colorectal cancer

Frontiers in Immunology
Background Early detection of colorectal cancer (CRC) is crucial for improving patient outcomes. Cell-free DNA (cfDNA) analysis has emerged as a promising non-invasive approach for cancer detection. This study aims to develop a machine learning algorithm leveraging cfDNA fragmentomic features to accurately ...
Shan, Lina, Xu, Dengyong, Chen, Jie, Liu, Wenjia, Lin, Ji, Bao, Juhang, Huang, Jianfei, Zhang, Hanqing, Zhao, Hanchen, Xue, Wei, Lin, Ziao, Bai, Bingjun   +11 more
openaire   +2 more sources

Distinct Features of Plasma Ultrashort Single-Stranded Cell-Free DNA as Biomarkers for Lung Cancer Detection [PDF]

, 2023
BackgroundUsing broad range cell-free DNA sequencing (BRcfDNA-Seq), a nontargeted next-generation sequencing (NGS) methodology, we previously identified a novel class of approximately 50 nt ultrashort single-stranded cell-free DNA (uscfDNA) in plasma ...
Lin, Chien-Chung, Zheng, David, Zhang, Liying, Swarup, Neeti, Kim, Yong, Wei, Fang, Aziz, Mohammad, Wong, David TW, Li, Feng, Chia, David, Kordi, Misagh, Yang, Szu-Chun, Huang, Wei-Lun, Cheng, Jordan C, Yeh, Yu-Min, Su, Wu-Chou, Pellegrini, Matteo   +16 more
core   +1 more source

Macromolecular Fragmentation on the Skin Surface: Formation Mechanisms, Evidence Limitations, and Potential Relevance for Skin Homeostasis

Cosmetics
The skin surface is a dynamic biochemical interface where proteins, polysaccharides, lipids, and microbial or environmental molecules are continuously exposed to ultraviolet(UV) radiation, oxidative stress, mechanical stimulation, pH variation, host ...
Keran Jia, Xiao Ning, Liya Song, Jin Cao
doaj   +1 more source

Cell-Free DNA Fragmentomics beyond Early Detection: A Narrative Review of Treatment Monitoring Applications in Solid Tumors

Cell-free DNA (cfDNA) fragmentomics the analysis of non-random fragmentation patterns reflecting chromatin architecture and epigenetic regulation has emerged as a powerful approach for non-invasive cancer detection.
Aakash M, Venkateswaramurthy N, Premkumar G   +2 more
core   +1 more source