Results 11 to 20 of about 27,832 (201)
Francisella and Antibodies [PDF]
Microorganisms, 2021 Immune responses to intracellular pathogens depend largely upon the activation of T helper type 1-dependent mechanisms. The contribution of B cells to establishing protective immunity has long been underestimated.
Klara Kubelkova, Ales Macela
doaj +3 more sources
Comparative Transcriptional Analyses of Francisella tularensis and Francisella novicida. [PDF]
PLoS ONE, 2016 Francisella tularensis is composed of a number of subspecies with varied geographic distribution, host ranges, and virulence. In view of these marked differences, comparative functional genomics may elucidate some of the molecular mechanism(s) behind ...
Siva T Sarva +3 more
doaj +4 more sources
Regulation of Francisella Tularensis Virulence [PDF]
Frontiers in Microbiology, 2011 Francisella tularensis is one of the most virulent bacteria known and a Centers for Disease Control and Prevention Category A select agent. It is able to infect a variety of animals and insects and can persist in the environment, thus Francisella spp ...
Shipan eDai +7 more
core +5 more sources
Genetic Manipulation of Francisella Tularensis [PDF]
Frontiers in Microbiology, 2011 Francisella tularensis is a facultative intracellular pathogen that causes the disease tularemia. F. tularensis subsp. tularensis causes the most severe disease in humans and has been classified as a select A agent and potential bioweapon.
Xhavit Zogaj, Karl E. Klose
core +6 more sources
Phenotypical and Genomic Characterization of the Mollusk Pathogen Francisella halioticida. [PDF]
MicrobiologyopenPhenotypic and genetic characterization of French isolates of Francisella halioticida and comparison with Canadian and Japanese strains. The study revealed similarities between FR22s and previous isolates but distinct differences with FR21. A major finding is the absence of the Francisella pathogenicity island in the less virulent isolate, FR22b ...
Bouras H +7 more
europepmc +2 more sources
De Novo Design of High-Affinity Miniprotein Binders Targeting Francisella Tularensis Virulence Factor. [PDF]
Angew Chem Int Ed EnglHybrid physics and deep‐learning enabled design methods identified miniprotein binders to Flpp3 (Francisella‐like lipoprotein), a key virulence factor from Francisella tularensis. Multiple candidates with nanomolar to picomolar binding affinities were obtained using yeast surface display screening and further experimental optimization.
Gokce-Alpkilic G +18 more
europepmc +3 more sources
Frontiers in Microbiology, 2011 In recent years, studies on the intracellular pathogen Francisella tularensis have greatly intensified, generating a wealth of new information on the interaction of this organism with the immune system. Here we review the basic elements of the innate and adaptive immune responses that contribute to protective immunity against Francisella species, with ...
Cowley, Siobhán C., Elkins, Karen L.
openaire +3 more sources
Emerging Infectious Diseases, 2022 Although Francisella tularensis is a well-known, highly virulent bacterium that causes tularemia in humans, other Francisella species have been associated with sporadic human infections. We describe a human cutaneous infection with bacteremia caused by F.
Aurélie Hennebique +9 more
doaj +1 more source
Comparative review of Francisella tularensis and Francisella novicida [PDF]
Frontiers in Cellular and Infection Microbiology, 2014 Francisella tularensis is the causative agent of the acute disease tularemia. Due to its extreme infectivity and ability to cause disease upon inhalation, F. tularensis has been classified as a biothreat agent. Two subspecies of F. tularensis, tularensis and holarctica, are responsible for tularemia in humans. In comparison, the closely related species
Kingry, Luke C., Petersen, Jeannine M.
openaire +2 more sources
Characterization of Francisella species isolated from the cooling water of an air conditioning system. [PDF]
, 2015 Strains of Francisella spp. were isolated from cooling water from an air conditioning system in Guangzhou, China. These strains are Gram negative, coccobacilli, non-motile, oxidase negative, catalase negative, esterase and lipid esterase positive.
Atwill, Edward +6 more
core +3 more sources