Although Francisella tularensis is a well-known, highly virulent bacterium that causes tularemia in humans, other Francisella species have been associated with sporadic human infections. We describe a human cutaneous infection with bacteremia caused by F.
Aurélie Hennebique +9 more
doaj +2 more sources
Francisella tularensis Subspecies holarctica and Tularemia in Germany
Tularemia is a zoonotic disease caused by Francisella tularensis a small, pleomorphic, facultative intracellular bacterium. In Europe, infections in animals and humans are caused mainly by Francisella tularensis subspecies holarctica.
Sandra Appelt +5 more
doaj +2 more sources
Presence of Francisella tularensis subsp. holarctica DNA in the Aquatic Environment in France
In 2018, the incidence of tularemia increased twofold in the west of France, with many pneumonic forms, suggesting environmental sources of infection. We investigated the presence of Francisellatularensis subsp.
Camille D. Brunet +5 more
doaj +2 more sources
Comparative Transcriptional Analyses of Francisella tularensis and Francisella novicida. [PDF]
Francisella tularensis is composed of a number of subspecies with varied geographic distribution, host ranges, and virulence. In view of these marked differences, comparative functional genomics may elucidate some of the molecular mechanism(s) behind ...
Siva T Sarva +3 more
doaj +4 more sources
Density-Dependent Prevalence of Francisella tularensis in Fluctuating Vole Populations, Northwestern Spain [PDF]
Self Archiving; https://wwwnc.cdc.gov/eid/page/copyright-and-disclaimers J.J.L.L., F.M., and R.R.P. held official licenses for trapping wildlife in Spain. Capture permits were provided by the Dirección General del Medio Natural, Junta de Castilla y León.
Anda, Pedro +9 more
core +5 more sources
The Francisella Type VI Secretion System
Francisella tularensisis subsp. tularensis is an intracellular bacterial pathogen and the causative agent of the life-threatening zoonotic disease tularemia.
Daniel L. Clemens +2 more
doaj +2 more sources
Phenotypical and Genomic Characterization of the Mollusk Pathogen Francisella halioticida. [PDF]
Phenotypic and genetic characterization of French isolates of Francisella halioticida and comparison with Canadian and Japanese strains. The study revealed similarities between FR22s and previous isolates but distinct differences with FR21. A major finding is the absence of the Francisella pathogenicity island in the less virulent isolate, FR22b ...
Bouras H +7 more
europepmc +2 more sources
The pentose phosphate pathway constitutes a major metabolic hub in pathogenic Francisella
Metabolic pathways are now considered as intrinsic virulence attributes of pathogenic bacteria and hence represent potential targets for anti-bacterial strategies.
Héloïse Rytter +14 more
openalex +3 more sources
De Novo Design of High-Affinity Miniprotein Binders Targeting Francisella Tularensis Virulence Factor. [PDF]
Hybrid physics and deep‐learning enabled design methods identified miniprotein binders to Flpp3 (Francisella‐like lipoprotein), a key virulence factor from Francisella tularensis. Multiple candidates with nanomolar to picomolar binding affinities were obtained using yeast surface display screening and further experimental optimization.
Gokce-Alpkilic G +18 more
europepmc +3 more sources
Pathogenicity and virulence of Francisella tularensis
Tularaemia is a zoonotic disease caused by the Gram-negative bacterium, Francisella tularensis. Depending on its entry route into the organism, F.
Manon Degabriel +3 more
semanticscholar +1 more source

