Evidence Suggesting That Francisella tularensis O-Antigen Capsule Contains a Lipid A-Like Molecule That Is Structurally Distinct from the More Abundant Free Lipid A. [PDF]
PLoS ONE, 2016 Francisella tularensis, the Gram-negative bacterium that causes tularemia, produces a high molecular weight capsule that is immunologically distinct from Francisella lipopolysaccharide but contains the same O-antigen tetrasaccharide.
Jason H Barker +3 more
doaj +1 more source
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. [PDF]
, 2010 Francisella tularensis, the causative agent of tularemia, infects host macrophages, which triggers production of the proinflammatory cytokines interleukin 1beta (IL-1beta) and IL-18. We elucidate here how host macrophages recognize F.
Alnemri, Emad S +12 more
core +3 more sources
Tularemia as a waterborne disease: a review
Emerging Microbes and Infections, 2019 Francisella tularensis is a Gram-negative, intracellular bacterium causing the zoonosis tularemia. This highly infectious microorganism is considered a potential biological threat agent.
Aurélie Hennebique +2 more
doaj +1 more source
Eficacia de un desinfectante sobre Vibrio ordalii, Vibrio anguillarum, Francisella sp. y Virus de la Necrosis Pancreática Infecciosa (IPNV), patógenos de salmón del Atlántico (Salmo salar) cultivado en Chile [PDF]
, 2011 Indexación: ScieloRESUMEN En el presente trabajo se evaluó la eficacia in vitro del desinfectante Duplalim®, una combinación sinérgica de glutaraldehído y sales de amonio cuaternario de cuarta generación, contra 4 patógenos de peces prevalentes de la ...
Avendaño-Herrera, R +2 more
core +2 more sources
Проблемы особо опасных инфекций, 2009 Considered are modern principles of prokaryotes classification, definition and limits of prokaryotic species as classification and identification unit, criteria of validity of scientific names of the microorganisms.
I. V. Gracheva +3 more
doaj +1 more source
Metagenomic-based Surveillance of Pacific Coast tick Dermacentor occidentalis Identifies Two Novel Bunyaviruses and an Emerging Human Ricksettsial Pathogen. [PDF]
, 2017 An increasing number of emerging tick-borne diseases has been reported in the United States since the 1970s. Using metagenomic next generation sequencing, we detected nucleic acid sequences from 2 novel viruses in the family Bunyaviridae and an emerging ...
Bouquet, Jerome +5 more
core +2 more sources
Early infection-induced natural antibody response
Scientific Reports, 2021 There remains to this day a great gap in understanding as to the role of B cells and their products—antibodies and cytokines—in mediating the protective response to Francisella tularensis, a Gram-negative coccobacillus belonging to the group of ...
Klara Kubelkova +4 more
doaj +1 more source
Microbiology Spectrum, 2023 Francisella tularensis is a highly infectious Gram-negative bacterial pathogen capable of animal-to-human transmission. Due to its remarkable pathogenicity and potential for widespread public health impact, F.
Ashley Clarke +7 more
doaj +1 more source
Francisella tularensis subsp. tularensis induces a unique pulmonary inflammatory response: role of bacterial gene expression in temporal regulation of host defense responses. [PDF]
PLoS ONE, 2013 Pulmonary exposure to Francisella tularensis is associated with severe lung pathology and a high mortality rate. The lack of induction of classical inflammatory mediators, including IL1-β and TNF-α, during early infection has led to the suggestion that F.
Kathie-Anne Walters +8 more
doaj +1 more source
Regulation of virulence in Francisella tularensis by small non-coding RNAs [PDF]
, 2011 Using a cDNA cloning and sequencing approach we have shown that Francisella tularensis expresses homologues of several small RNAs (sRNAs) that are well-conserved among diverse bacteria.
Alain Charbit +6 more
core +2 more sources