PCR and sequencing based methods for detection and typing of pathogenic microorganisms [PDF]
The potential use of bacteria and viruses as biological terror weapons makes certain highly pathogenic microorganisms a worldwide public health threat.
Wahab, Tara
core +1 more source
Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu +5 more
wiley +1 more source
Phenotypical and Genomic Characterization of the Mollusk Pathogen Francisella halioticida
Phenotypic and genetic characterization of French isolates of Francisella halioticida and comparison with Canadian and Japanese strains. The study revealed similarities between FR22s and previous isolates but distinct differences with FR21. A major finding is the absence of the Francisella pathogenicity island in the less virulent isolate, FR22b ...
Hélène Bouras +7 more
wiley +1 more source
Infection of Mammalian Hepatocytes by Francisella tularensis LVS [PDF]
Francisella tularensis, the causative agent of Tularemia, is a facultative intracellular parasite. The goal of this project is to examine how F. tularensis infects and replicates within mammalian cells, and the impact of such an infection upon the ...
Vasioutovitch, Pavel
core
Diversity of Coxiella-like and Francisella-like endosymbionts, and Rickettsia spp., Coxiella burnetii as pathogens in the tick populations of Slovakia, Central Europe [PDF]
Ticks are important vectors of pathogens affecting humans and animals worldwide. They do not only carry pathogens but diverse commensal and symbiotic microorganisms are also present in ticks.
Al-Deeb +60 more
core +1 more source
Acinetobacter baumannii transposon insertion mutant strains ΔpilA and ΔtrxA display marked reductions of surface pili. The PilA (a major pilin protein) and TrxA (thioredoxin A) deficient bacteria also show attenuation in pathogenesis including the reduction of intestinal bacterial attachment, increased phagocytic uptake and decreased mortality from ...
Jadelynn Aki +11 more
wiley +1 more source
Zoonotic Disease Transmission May Be Linked to Host Co‐Occurrence Network Topology
A global analysis of zoonotic host co‐occurrence networks identified 22 networks from five continents (A) and 87 hosts from 16 orders of mostly birds but also mammals (B) as having a high potential for disease transmission. ABSTRACT Most human pathogens are zoonotic, transmitted from vertebrate hosts to humans.
Patrick T. Stillson +3 more
wiley +1 more source
Immunobiological Properties of Francisella tularensis Antigen Complexes
Carried out are the studies of preparations of Francisella tularensis antigen complexes, obtained from the producer strains of different subspecies (holarctica, nearctica, mediasiatica, novicida).
E. M. Kuznetsova +7 more
doaj +1 more source
Working correlates of protection predict SchuS4-derived-vaccine candidates with improved efficacy against an intracellular bacterium, Francisella tularensis [PDF]
Roberto De Pascalis +8 more
openalex +1 more source
Type VI secretion: a beginner's guide [PDF]
Type VI secretion is a newly described mechanism for protein transport across the cell envelope of Gram-negative bacteria. Components that have been partially characterised include an IcmF homologue, the ATPase ClpV, a regulatory FHA domain protein and ...
Akeda +47 more
core +1 more source

